Kymera Therapeutics · 16 hours ago
Director, Cheminformatics and Predictive Modeling
Greater Boston
Full-time
Hybrid
Director/Executive
$195K/yr - $275K/yr
8+ years expKymera Therapeutics is a clinical-stage biotechnology company focused on pioneering targeted protein degradation to develop innovative medicines. The Director of Cheminformatics and Predictive Modeling will lead the development of machine learning models and integrate them with molecular modeling to enhance drug discovery processes.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Lead the development and deployment of machine learning models for potency, selectivity, ADME, and safety endpoints to accelerate molecular design and optimization
Integrate machine learning with molecular modeling and generative design approaches to enable a high-throughput molecular design engine
Partner cross-functionally to define and execute AI/ML strategies to accelerate the DMTA cycle and data-driven decision-making processes
Collaborate closely with IT/Informatics and Research teams to ensure robust data capture, analysis pipelines, and scalable molecular and predictive modeling infrastructure
Advance computational discovery and design capabilities by evaluating, piloting, and adopting novel and emerging AI and modeling technologies
Qualification
Required
PhD or equivalent experience in Computational Chemistry, Cheminformatics, Machine Learning, or a related field
8+ years of experience in biotech or pharma applying ML to drug discovery problems
Deep hands-on experience with ML methods applied to molecular or chemical data
Strong understanding of chemical representations, structure–property relationships, and ADME/Tox principles
Proven track-record of successful application of ML in molecular design
Experience collaborating with cross-functional scientific teams
Experience with generative models, active learning, and multi-objective optimization
Strong understanding of cloud-based ML infrastructure
Track record of publications, patents, and impacts in drug discovery
Benefits
Eligibility for annual bonus
Equity participation
Comprehensive benefits
Company
Kymera Therapeutics
Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
51-200 employees
H1B Sponsorship
Kymera Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (2)
2023 (4)
2022 (3)
2021 (3)
Funding
Current Stage
Public CompanyTotal Funding
$1.96BKey Investors
Biotechnology Value FundAtlas Venture
2025-12-10Post Ipo Equity· $602M
2025-06-26Post Ipo Equity· $250.8M
2024-08-19Post Ipo Equity· $225M
Leadership Team
Nello Mainolfi
Founder, President and Chief Executive Officer
Jeremy Chadwick
Chief Operating Officer
Recent News
2026-01-16
2026-01-11
Company data provided by crunchbase