Dispatch Bio · 14 hours ago
Manager, Biomarker Operations
Philadelphia, PA
Full-time
Onsite
Senior Level
5+ years expDispatch Bio is a startup biotechnology company dedicated to engineering a universal treatment across solid tumors. The Biomarker Operations Manager will be responsible for the operational execution of the biomarker plan defined by Translational Sciences across preclinical and clinical programs, ensuring high-quality, on-time delivery of biomarker activities and supporting clinical development and regulatory objectives.
BiotechnologyHealth CareTherapeutics
Hiring Manager
Erica Arkin
Responsibilities
Plan, execute, and track biomarker activities across clinical studies, including sample collection, handling, storage, shipment, testing, and data delivery
Translate biomarker strategy into operational plans, timelines, and budgets
Support implementation of exploratory, pharmacodynamic, pharmacokinetic, and safety biomarkers
Oversee biospecimen logistics, including site training, sample collection kits, chain of custody, and reconciliation
Ensure compliance with protocol, ICH/GCP, and applicable biosafety and ethical requirements
Maintain accurate sample inventories and documentation
Manage external vendors (e.g., central labs, specialty labs, CROs)
Oversee contracts, SOWs, timelines, deliverables, and budgets for biomarker-related vendors
Serve as primary operational point of contact for biomarker vendors
Oversee internal lab sample receipt, accessioning, storage, and chain-of-custody documentation
Partner closely with Clinical Operations, Translational Sciences, Research, Data Management, Regulatory, and Quality teams
Support protocol development, informed consent language, and clinical operations manuals related to biomarker activities
Contribute to study team meetings and program-level planning
Ensure timely and accurate transfer of biomarker data to internal teams and data management systems
Support data review, query resolution, and integration with clinical datasets
Contribute to clinical study reports, regulatory submissions, and scientific communications
Develop and maintain work instructions, SOPs, workflows, and templates for biomarker operations
Identify opportunities to improve efficiency, quality, and scalability of biomarker execution
Support inspection and audit readiness related to biomarker activities
Qualification
Required
Bachelor's degree in life sciences or related field (advanced degree preferred)
At least 5 years of experience in biomarker operations, translational research, clinical operations, or laboratory project management
Hands-on experience managing biomarker activities in clinical trials
Strong understanding of biospecimen handling, laboratory workflows, and clinical trial operations
Experience working with external vendors and CROs
Excellent organizational, communication, and problem-solving skills
Preferred
Experience in oncology, cell therapy, gene therapy, or immunology
Familiarity with regulatory expectations for biomarker data (e.g., FDA, EMA)
Experience in early-stage or small biotech environments
Knowledge of sample tracking systems, clinical data standards and LIMS (e.g., Benchling)
Benefits
Excellent coverage for medical, vision, and dental
401(k) with generous contribution
Life insurance
Flexible PTO policy
Additional substantial benefits
Company
Dispatch Bio
Dispatch Biotherapeutics develops immunotherapy that treats solid tumors, which could significantly advance cancer treatment options.
51-200 employees
H1B Sponsorship
Dispatch Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
Funding
Current Stage
Growth StageTotal Funding
$216M2025-07-23Series A· $216M
2023-01-01Seed
Leadership Team
Mauro Avanzi
Chief Medical Officer
Recent News
Company data provided by crunchbase