Novartis · 16 hours ago
Associate Director, Biotherapeutic Engineering & Bioconjugation
San Diego, CA
Full-time
Onsite
Lead/Staff, Director/Executive
$153K/yr - $283K/yr
10+ years expNovartis is a leading company in the development of innovative medicines, and they are seeking an Associate Director of Biotherapeutic Engineering & Bioconjugation to lead the Biotherapeutic Engineering and Bioconjugate group. This role involves driving a diverse portfolio of pipeline programs and providing scientific leadership in the development of recombinant therapies and bioconjugates.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Leads a team of 4 labs and 15-20 subject matter experts on the San Diego site responsible to drive recombinant therapies to patients
Establishes mid- and long-term goals, plan of action and implementation for the BEC team (e.g. annual objectives) in line with BRC and BR strategy and objectives. Identifies and addresses obstacles to success both within and across departments
Integrating expertise from multiple sites and units, develops strategy and provides scientific leadership at a technical level in our core deliverable areas (Antibody Oligo Conjugates, Antibody Drug Conjugates, multispecifics)
Represents BEC as BEC Site Head for San Diego including managing the budget of the BEC unit in collaboration with global counterparts in order to meet BRC targets
Sets strategy, implements and manages outsourcing for the local BEC team
Interfaces with downstream development colleagues to bring lead candidates towards full development
Collaborates and coordinates activities with other global BRC and BR units
Offers innovative approaches to scientific questions and troubleshoots efforts to develop recombinant protein and antibody-based therapeutics in immune cell engagers, regulated/activatable antibodies, multispecific antibodies, and ADCs and AOCs
Identifies Disease Area’s unmet needs and collaborates for a novel therapeutic solution
Ensure compliance for contemporaneous and accurate documentation of scientific activities and for ethical, health and safety, and quality assurance metrics
Qualification
Required
PhD with at least 10 years relevant experience as an expert in protein engineering
Demonstrated ability to recruit, retain and develop diverse and agile associates with different expertise, seniority to ensure long term talent development and succession planning
Background in leading and mentoring a research group consisting of associates of all levels and acting as a manager of managers
Proficiency in antibody molecular biology, protein expression, purification, chemical modification, analytics, biophysical characterization, functional characterization and functional assay design and interpretation
Familiarity with all aspects of antibody discovery, optimization, production, and transition to development/manufacturing groups
Familiarity with preclinical and early clinical development of biotherapeutics. Awareness of biomarker development, clinical assays, manufacturing, safety profiling, and clinical trial design
Preferred
Prior experience with computational protein design/modelling and structure analysis as well as library-based approaches to attenuate function and developability properties of protein therapeutics
Proven experience developing and innovating on mixed modality therapeutics. Expertise designing and optimizing Antibody-Oligo Conjugates is highly desired
A demonstrated track record of success as judged by publications and patents
Highly collaborative spirit inside and outside of department to advance programs to clinic; good communication skills, creativity, and multi-tasking in a fast-paced environment
Ability to master new subjects and assess diverse scientific content related to the broader field of biologics drug discovery and development in a broad range of disease areas
Benefits
Health, life and disability benefits
A 401(k) with company contribution and match
A generous time off package including vacation, personal days, holidays and other leaves
Company
Novartis
Novartis is a pharmaceutical company that researches and develops medicines for serious diseases to improve and extend people's lives.
10001+ employees
H1B Sponsorship
Novartis has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (27)
2023 (23)
2022 (27)
2021 (31)
2020 (25)
Funding
Current Stage
Public CompanyTotal Funding
$2.49BKey Investors
Bill & Melinda Gates Foundation
2024-06-19Post Ipo Debt· $2.49B
2018-02-14Grant· $6.5M
2000-05-19IPO
Leadership Team
Daniel Grant
Vice President & Global Program Head
John von Brachel
VP, Head of Content Lab
Recent News
2026-01-23
2026-01-23
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