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Elanco · 5 hours ago

Principal Research Scientist, Bioanalytical (Large Molecule)

Indianapolis, IN

Full-time

Hybrid

Senior Level, Lead/Staff

5+ years exp

Elanco is a global leader in animal health, dedicated to innovation in preventing and treating diseases in farm animals and pets. The Principal Research Scientist will serve as the bioanalytical subject matter expert for large molecule programs, leading assay development and execution to support early research and development efforts.

ManufacturingPetSupply Chain Management

H1B Sponsor Likely

Responsibilities

Lead the design, development, and implementation of bioanalytical assays (e.g., MSD, ELISA/LBA, cell-based assays) to support PK, biomarker, and immunogenicity (ADA) assessment for large molecule modalities

Serve as the bioanalytical lead on cross-functional project teams, providing scientific and strategic guidance from early research through clinical development

Mentor and develop junior scientists and provide scientific oversight to CRO partners, ensuring technical excellence and knowledge transfer

Oversee assay transfer, validation, and sample analysis at CROs, reviewing protocols, data, and reports for quality, compliance, and scientific rigor

Champion new technologies, troubleshoot complex bioanalytical challenges, and ensure all activities meet regulatory and quality standards (FDA, EMA, ICH)

Qualification

Bioanalytical assay developmentLarge molecule therapeuticsRegulatory guidelines knowledgeBiomarker assay developmentCross-functional leadershipMentoring skillsCommunication skills

Required

Ph.D. in Immunology, Biochemistry, or related field with 5+ years of relevant industry experience, or

M.S. with 8+ years of relevant industry experience, or

B.S. with 10+ years of relevant industry experience

Extensive hands-on experience developing and executing PK and immunogenicity assays for large molecule therapeutics

Demonstrated understanding and application of global bioanalytical regulatory guidelines

Proven ability to lead bioanalytical workstreams in a matrixed, cross-functional environment

Preferred

Experience managing and overseeing bioanalytical activities at CROs

Biomarker assay development experience

Strong people leadership skills with a track record of mentoring and developing scientific talent

Excellent written and verbal communication skills, with the ability to clearly convey complex scientific and regulatory concepts

Company

Elanco

Glassdoor3.6

Elanco is an animal health company that manufactures and markets a diverse range of products to promote animal health and well-being.

Founded in 1954

Greenfield, Indiana, USA

5001-10000 employees

https://www.elanco.com

H1B Sponsorship

Elanco has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (9)

Funding

Current Stage

Public Company

Total Funding

$252.86M

Key Investors

AncoraBill & Melinda Gates Foundation

2023-12-30Post Ipo Equity· $250M

2018-09-19IPO

2017-05-24Grant· $2.86M

Leadership Team

Dave Kinard

Executive Vice President Human Resources, Corporate Affairs & Administration

Jennifer Black

Senior Director, Global Indirect Procurement

Recent News

PR Newswire

Elanco Receives USDA Approval for Befrena™ (tirnovetmab), a New Anti-IL31 Monoclonal Antibody Injection Targeting Canine Allergic and Atopic Dermatitis

2026-01-03

thefly.com

Elanco receives USDA approval for Befrena

2026-01-03

thefly.com

Elanco's Credelio Quattro tablets granted FDA conditional approval

2025-12-18

Company data provided by crunchbase