Broad Institute of MIT and Harvard · 2 hours ago
Research Scientist I
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$88K/yr - $124K/yrThe Broad Institute of MIT and Harvard is seeking a highly motivated Research Scientist to lead a multi-year project focused on RNA sensor design and high-throughput brain cell targeting. This role involves driving a research program that integrates experimental and computational approaches while collaborating with various teams and mentoring junior scientists.
BiotechnologyClinical TrialsLife Science
Responsibilities
Independently design and lead a research program to develop RNA sensor–based strategies for high-throughput, cell-type-specific targeting in the brain
Design, execute, and analyze pooled genetic and molecular screens to identify and optimize targeting strategies
Develop and optimize experimental pipelines spanning molecular engineering, delivery, screening, and readout
Integrate experimental results with computational analysis to guide iterative design and discovery
Collaborate with internal Broad Institute teams and external academic collaborators to advance shared scientific goals
Lead and mentor graduate students and research associates contributing to the project
Contribute to manuscripts, presentations, grant reports, and dissemination of new technologies
Support documentation, reproducibility, and potential intellectual property generation related to new methods
Qualification
Required
Ph.D. (or equivalent) in molecular biology, bioengineering, neuroscience, genomics, or a related field
Demonstrated ability to independently lead complex research projects from conception through execution and publication
Strong experience with pooled genetic or molecular screens, programmable targeting strategies, or delivery technologies
Solid experimental background with comfort working across molecular, cellular, and systems-level approaches
Experience analyzing large-scale screening or genomics datasets; familiarity with computational or statistical analysis workflows is strongly preferred
Proven mentorship or team-leadership experience, or clear potential to supervise and guide junior scientists
Excellent communication, organizational, and collaborative skills in a fast-paced, interdisciplinary research environment
Preferred
Familiarity with computational or statistical analysis workflows
Benefits
Medical, dental, vision, life, and disability insurance
401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
Employee assistance program
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
Founded in 2003
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
Research & Development World
2026-01-22
Broad Institute of MIT and Harvard
2026-01-17
2025-12-02
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