Arcellx · 10 hours ago
Scientist, Immunogenicity Assay Development (Contractor)
Rockville, MD
Full-time, Contract
Onsite
Senior Level
5+ years expArcellx is a public, clinical-stage biotechnology company focused on engineering innovative immunotherapies for cancer and other incurable diseases. The Scientist in Immunogenicity Assay Development will build in vitro immunogenicity assays, document assay development, and contribute to pipeline programs while collaborating with cross-functional teams.
BiopharmaBiotechnologyHealth CareLife SciencePharmaceutical
Responsibilities
Build an in vitro immunogenicity assay using HLA-Typed PBMCs, assessing T-cell activation and proliferation as measured through flow cytometry. Through the use of clinical benchmarks and in-house data, build a relative risk assessment for clinical immunogenicity based on these in vitro
Careful documentation of assay development, including drafting SOPs and electronic lab notebook entries
Contribute to one or more pipeline programs, working collaboratively with cross-functional teams to ensure the timely generation and dissemination of critical program data to enable data-driven decisions
Design and execute experiments independently with minimal supervision, as well as effectively plan and organize work activities and prioritize task completion
Other duties as assigned
Qualification
Required
BS and 5+ years or MS and 2+ years of assay development experience within the pharmaceutical industry setting
Expertise in cell culture with a focus on manipulating PBMCs and T-cells, including activation, purification, and cryopreservation
Working knowledge of immunology and a familiarity with markers of activation for phenotyping of T-cells by flow cytometry
Expertise in flow cytometry panel design and optimization
Expertise in immune cell assays including multiparameter flow cytometry and in vitro assays to determine T-cell activation or proliferation (e.g., BrdU incorporation). Preferably experience with BD instruments or Cytek Aurora for flow cytometry
Proficient in common software, including GraphPad Prism, FlowJo, and Office suite
Commitment to ethical scientific investigations and rigorous experimental methods
Ability and desire to multitask and function in a fast-paced environment
Interpersonal skills that promote a collaborative and productive lab environment
Effective and efficient written and oral communication skills
Company
Arcellx
Arcellx is a clinical-stage biotechnology company that provides patients with immune cell therapies.
51-200 employees
H1B Sponsorship
Arcellx has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (4)
2022 (2)
Funding
Current Stage
Public CompanyTotal Funding
$622MKey Investors
Kite Pharma
2023-11-15Post Ipo Equity· $200M
2022-12-09Post Ipo Equity· $100M
2022-06-15Post Ipo Equity· $112M
Leadership Team
Michelle Gilson
Chief Financial Officer
Brad Gliner
Vice President, Clinical Research and Regulatory Affairs
Recent News
2025-12-11
Company data provided by crunchbase