Amgen · 3 hours ago
Senior Scientist - Immunology/Immunogenicity
Thousand Oaks, CA
Full-time
Onsite
Mid, Senior Level
4+ years expAmgen is a biotechnology company dedicated to serving patients living with serious illnesses. The Senior Scientist in Immunology/Immunogenicity will perform various in vitro assays to assess the immunogenic risk of protein therapeutics, collaborating closely with multiple teams to drive project execution and support individual growth.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Perform various cell-based assays using primary human cells, such as dendritic cell or B cell co-culture with T cells using T cell proliferation, cell surface expression, and cytokine production as a readout
Development novel in vitro assays to assess immunogenic risk
Collaborate with colleagues to execute MHC-associated peptide proteomics (MAPPs) experiments to identify potential T cell epitopes within protein therapeutic candidates
Design and/or modify assays based on the mechanism of action of the drug candidate
Implement the cell-based assays using an automated, high throughput platform
Generate data, interpret, and summarize results for presentation at internal meetings as needed
Summarize results into study reports for incorporation into regulatory documents
Mentor a lab-based scientific team, driving project execution while supporting individual growth and long-term career development
Qualification
Required
Doctorate Degree
Or
Master's degree and 2 years in Immunology or related experience
Or
Bachelor's degree and 4 years in Immunology or related experience
Preferred
PhD with experience in the field of immunology with specific training in T cell and/or dendritic cell (DC) biology; T cell memory recall assays
Technical expertise in cell culture, multi-color flow cytometry, complex cell-based functional assays using primary cells and cell-lines, internalization assays, and MAPPS
Knowledge of liquid handing and robotic platform
Strong verbal and written communication skills
Ability to work independently in a diverse, cross-functional team environment
High degree of flexibility to adapt to different projects and shifting priorities
Benefits
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-24
2026-01-22
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