Predicta Biosciences · 1 day ago
Senior Research Scientis
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$120K/yr - $180K/yr
5+ years expPredicta Biosciences is a precision oncology company that integrates cutting-edge multiomics and liquid biopsies to create innovative diagnostic and therapeutic products. They are seeking a highly motivated Senior R&D Scientist to lead assay development efforts focused on NGS technologies, including single-cell RNA-seq and whole genome sequencing, while collaborating with cross-functional teams to improve blood-based cancer diagnostic capabilities.
Artificial Intelligence (AI)BiotechnologyHealth DiagnosticsLife ScienceTherapeutics
Responsibilities
Design, develop, and optimize molecular assays for diagnostic applications with a focus on immune characterization and an emphasis on single-cell RNA-based solutions
Contribute to development and optimization of NGS workflows, including library preparation, sample processing, and quality control
Evaluate and implement new technologies, reagents, and platforms to improve assay performance, robustness, and scalability
Plan and execute experiments independently, analyze data, and clearly communicate results to internal stakeholders
Collaborate closely with the R&D and computational biology teams to ensure seamless integration of wet-lab and analytical workflows
Develop and document standard operating procedures (SOPs), protocols, and technical reports suitable for regulated environments
Mentor junior scientists and contribute to building best practices within the R&D organization
Support technology transfer from R&D into product development and clinical operations as needed
Other duties as assigned
Qualification
Required
PhD (or BS/MSc with significant industry experience) in molecular biology, biochemistry, genetics, bioengineering, or a related field
5+ years of hands-on laboratory experience in molecular biology and assay development, preferably in a cutting-edge research/R&D environment
Deep expertise with single-cell RNA-seq technologies (e.g. scRNA-seq, scWGS, scATAC-seq, scMultiomics, etc.), associated sample preparation methods, and quality control
Deep expertise in NGS technologies, including library prep, sequencing platforms, and workflow optimization
Strong experimental design, troubleshooting, and data interpretation skills
Demonstrated success working with cross-functional, fast-moving research or startup environments and collaborating with computational scientists
Outstanding written and verbal communication skills
Ability to handle several fast-paced projects concurrently
Demonstrated curiosity and scientific rigor with excellent problem-solving skills
Ability to engage in crucial conversations – providing and receiving feedback
Preferred
Solid working knowledge of immunology, particularly as it relates to immune-cell phenotyping
Background in immunology, immuno-oncology, or immune-mediated diseases
Experience developing assays intended for clinical or regulated use (e.g., CLIA, CAP, or FDA-regulated environments)
Familiarity with computational methods for analysis of single-cell and other NGS data, especially for quality control
Prior experience bringing assays from early research through to product development
Experience with automation of cell and molecular biology assays, especially sample extraction and NGS library preparation
Benefits
10% bonus opportunity
Equity
Flexible time off
401k Plan
Medical, dental and vision plans that are 90% paid by Predicta
Partially company funded HSA
Company
Predicta Biosciences
Predicta Biosciences provides molecular diagnostics and immunotherapeutic discovery services for hematological diseases.
11-50 employees
Funding
Current Stage
Early StageTotal Funding
$28.6MKey Investors
Engine Ventures
2025-10-01Series A· $23.4M
2024-07-16Seed· $5.2M
Leadership Team
Brian McKernan
Chief Executive Officer
Recent News
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