Pfizer · 9 hours ago
Scientist, LCMS PK Bioanalytical
Pfizer is a leading biopharmaceutical company, and they are seeking a Scientist to join their PK LCMS group in Andover. The role involves developing and qualifying LCMS assays for biotherapeutics and collaborating with multidisciplinary teams to support drug discovery and development.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Responsible for the development, qualification and implementation of PK/PD assays using mass spectrometry in support of discovery and preclinical projects
Works with group leads or other discovery and regulated bioanalytical team members and project team members to accomplish goals
Participates in technology development and implementation by exploring new workflows, including automation, high throughput sample preparation and instrumentation in protein quantitation, to expand the group’s PK LCMS bioanalytical capabilities
Participate in all phases of mass spectrometry laboratory operations including technology evaluations, the development of sample preparation and separation methods, data analysis, interpretation, reporting and follow up discussions with the project teams on utilizing the data in appropriate decision making
Ensure all tasks and responsibilities are carried out according to scientific and ethical standards e.g. responsible for electronic notebook record keeping; QC and peer review of data and reports
Qualification
Required
MS with have 4 to 6 years of relevant work experience, ideally mostly in industry (or BS/BA with 6 to 8 years of experience)
Expertise in development, characterization, and implementation of bioanalytical LCMS assays
Experience in the operation and troubleshooting of LCMS instrumentation and associated operating/data analysis software including Skyline, Analyst, Sciex OS and Xcalibur
Hands-on experience of biological sample preparation procedures for quantitative LCMS assays on biotherapeutics
Knowledge of writing scripts to set up methods for automated liquid handler system
Knowledge of protein biochemistry of therapeutic antibodies, fusion proteins or ADCs
Preferred
Expertise in quantitative tissue bioanalysis and extraction methodologies of large molecules
Expertise in biological sample preparation techniques (immunoaffinity, tryptic digestion, tissue processing, conjugation, etc) of various biofluids
Ability to work both independently and as part of a team, multitasking multiple programs
Experience working in a regulated bioanalytical laboratory and knowledge of GLP's is a plus
Knowledge to implement AI tools to facilitate data visualization, bioanalytical assay development and optimization
Benefits
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Company
Pfizer
Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.
Funding
Current Stage
Public CompanyTotal Funding
$38BKey Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B
Recent News
2026-01-25
Pharma Letter
2026-01-25
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