Eli Lilly and Company · 8 hours ago
Associate Scientist - LNP Process Development
US, Boston MA
Full-time
Onsite
Mid Level
$71K/yr - $187K/yr
4+ years expEli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana, dedicated to making life better for people around the world. They are seeking an Associate Scientist in LNP Process Development to join their Gene Therapy Team, responsible for inventing and advancing novel gene therapy reagents. The role involves implementing formulation studies, conducting characterization of formulations, and supporting process optimization.
BiotechnologyHealth CareMedicalPharmaceutical
No H1B
Responsibilities
Implement LNP/TNP formulation studies using bench-scale and pilot-scale equipment (NanoAssemblr, T-mixers, impinging jet mixers)
Perform downstream processing operations including tangential flow filtration (TFF), buffer exchange, and concentration
Conduct routine and non-routine characterization of LNP/TNP formulations to assess physical, chemical, and functional properties
Support the development and optimization of targeted lipid nanoparticle (TNP) formulation processes
Assist with process characterization studies to understand the impact of process parameters on product quality
Contribute to scale-up activities by performing experiments at increasing manufacturing scales
Engage in technology transfer activities
Qualification
Required
Bachelor's degree in Chemistry, Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or related fields with 4+ years of relevant industrial experience
OR Master's degree with 2+ years of relevant industrial experience
Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1
Preferred
Recent hands-on experience with lipid nanoparticle or liposome formulation in an industrial or academic research setting
Proficiency with small-scale LNP formulation using microfluidic mixing systems (e.g., Precision NanoSystems Ignite etc.)
Experience with mid-scale mixing technologies (T-mixing, impinging jet mixing) is highly desirable
Hands-on experience with tangential flow filtration (TFF) systems for nanoparticle purification and concentration
Strong working knowledge of LNP characterization techniques: Particle size and polydispersity (DLS), Surface charge characterization (zeta potential, ELS), Nucleic acid quantification (Ribogreen, absorbance methods), Encapsulation efficiency determination, Solution properties (pH, osmolality, appearance)
Benefits
Company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
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