Verge Genomics · 15 hours ago
Principal/Director, Computational Biology
United States
Full-time
Remote
Lead/Staff, Director/ExecutiveVerge Genomics is transforming drug discovery through artificial intelligence and proprietary human data. The Principal/Director, Computational Biology will lead the company's computational biology efforts, delivering insights to biopharma partners and driving their R&D decisions.
BiotechnologyGeneticsHealth CareMachine LearningNeuroscience
Responsibilities
Deliver biological insights on therapeutic candidates and disease biology from the analysis of multi-modal data (transcriptomics, genetics, and clinical data)
Translate high-level business objectives into a scientific workplan
Synthesize diverse datasets to generate and evaluate hypotheses for target prioritization, mechanism-of-action identification, indication expansion, repositioning, biomarker discovery, and patient enrichment
Present results to external stakeholders to drive pharma R&D decisions
Develop and validate benchmarks to evaluate performance of AI models on translational tasks
Interpret and analyze the output of AI foundation models
Translate between biological domain knowledge and machine learning objectives
Qualification
Required
PhD in computer science, computational biology, AI/ML, applied statistics, biophysics, or related field, or MS in related field with exceptional professional experience
Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data
Deep expertise with the multi-omic data integration (transcriptomics, genetics, proteomics, clinical data) and systems biology workflows (gene network, pathway enrichment analysis)
Track record of delivering novel translational insights that have influenced pharma/biotech R&D decisions (e.g. target discovery, biomarker identification, patient stratification)
Exceptional data visualization skills
Experience leading cross-functional projects with multiple parties including biologists, engineers, AI researchers, and external collaborators
Excellent coding skills in Python. A demonstrable portfolio (e.g., GitHub, research code, or shared notebooks) is highly preferred
Domain knowledge with advanced AI approaches and experience applying them to a biological context
Excellent communication skills, including explaining complex scientific concepts to cross-functional stakeholders using plots, documents, and presentations
Ability to thrive in uncertainty with frequently changing priorities
Deep alignment with our values
A passion for making an impact on patients
Preferred
A demonstrable portfolio (e.g., GitHub, research code, or shared notebooks) is highly preferred
Company
Verge Genomics
Verge Genomics uses machine learning and human genomics to accelerate drug discovery.
Founded in 2015
51-200 employees
Funding
Current Stage
Growth StageTotal Funding
$134.12MKey Investors
BlackRockThresholdIA Ventures
2023-07-01Series Unknown
2021-12-16Series B· $98M
2018-07-17Series A· $32M
Leadership Team
Alice Zhang
CEO & Co-founder
Victor Hanson-Smith
Distinguished Scientist, Head of Computational Biology
Recent News
2025-06-02
Company data provided by crunchbase