Gilead Sciences · 18 hours ago
Sr Associate Scientist, Analytical Ops
San Francisco Bay Area
Full-time
Onsite
Senior Level
$127K/yr - $164K/yrGilead Sciences is a leading company dedicated to creating a healthier world by tackling significant health challenges. They are seeking a highly motivated Postdoctoral Research Fellow to join their Analytical Development organization, focusing on developing advanced spectromicroscopy strategies to characterize long-acting injectable drug depots and understand their behavior in tissues.
BiopharmaBiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Develop and optimize Raman, FTIR, OPTIR, and MALDI MS methods to characterize depot chemistry and solidstate forms across synthetic media and exvivo tissues
Perform stressinduced solid form transition studies (pH, oxidative stress, moisturedriven transformations) for model LAI systems
Build machinelearning and chemometric models (CLS, PLS, PCA, imagebased segmentation) to map drug distribution, degradation, and polymorphic transitions
Characterize drug depots in porcine dermis, fat, and muscle tissue to assess intissue transformations and correlate analytical findings with histopathology and ISR outcomes
Integrate multimodal datasets (Raman/IR/MALDI) into unified chemical imaging workflows to support formulation development
Collaborate closely with Formulation, DMPK, DPP, and Toxicology teams on crossfunctional LAI development
Present research in internal forums and contribute to highimpact external publications and conferences
Qualification
Required
PhD in Chemistry, Chemical Engineering, Pharmaceutical Sciences, Materials Science, Optics Science, Biomedical Engineering, Mechanical Engineering or related discipline
Hands on experience with Raman and/or FTIR spectroscopy
Proficiency in Python and/or MATLAB for spectroscopic data processing,multivariate analysis, and deep learning for image segmentation
Strong scientific curiosity, problemsolving ability, and independent research skills
Demonstrated track record of conference presentations or peerreviewed publications
Preferred
Experience with techniques such as OPTIR, digital microscopy, fluorescence microscopy, quantitative phase microscopy, SEM/EDS, XRPD, MALDIIMS, HPLC, LCMS
Experience with building and maintaining advanced or non-linear spectroscopy/microscopy instruments
Background in solidstate characterization, LAI formulation, or tissuebased imaging workflows
Familiarity with chemometric platforms (e.g., PLS Toolbox)
Excellent communication skills and ability to work in a matrixed, multidisciplinary environment
Benefits
Company-sponsored medical, dental, vision, and life insurance plans
Company
Gilead Sciences
Gilead Sciences is a biopharmaceutical company that discovers, develops, manufactures and commercializes therapies for critical diseases.
Founded in 1987
10001+ employees
H1B Sponsorship
Gilead Sciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (269)
2024 (241)
2023 (222)
2022 (208)
2021 (235)
2020 (187)
Funding
Current Stage
Public CompanyTotal Funding
$4.41BKey Investors
Abingworth
2024-11-13Post Ipo Debt· $3.5M
2024-02-29Post Ipo Equity· $210M
2023-09-07Post Ipo Debt· $2B
Leadership Team
Keeley Wettan
Senior Vice President, Legal
Patrick Loerch
Senior Vice President, Clinical Data Science
Recent News
2026-01-23
GlobeNewswire
2026-01-22
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