Postdoctoral Fellow-MSH-12300-137 jobs in United States
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Mount Sinai Health System · 10 hours ago

Postdoctoral Fellow-MSH-12300-137

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow in the Hematology and Medical Oncology department. The role involves engaging in translational cancer research focused on breast cancer, utilizing various approaches to understand drug resistance and developing novel therapeutic strategies.

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H1B Sponsor Likelynote

Responsibilities

The researcher will be engaged in translational cancer research projects focused on regulators of growth, survival and drug resistance of breast and other cancers, as well as their microenvironment, especially immune effectors
The researcher will use a broad range of approaches (genetic, cell biological and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy treatments and metastasize
The projects also examine novel mechanisms that contribute to the growth and metastases of triple negative breast cancers
The researcher will utilize patient-derived xenograft models of breast cancer and organoid cultures to screen and validate novel therapeutic strategies in collaboration with chemical biologists
The researcher will also study how the immune microenvironment regulates response of breast and other cancers to chemotherapy/targeted therapies
The researcher will be expected to design and conduct experiments, be responsible for accurate record keeping and contribute to overall maintenance of the laboratory

Qualification

Cancer cell biologyMolecular biologyMouse handlingFlow cytometryCell cultureLab record keepingMicroscopyWestern BlotQPCRDNA preparationLentivirus productionOrganoid development

Required

Background in cancer cell biology/models, genetics, molecular biology, biochemistry, or immunology required
Ph.D or MD/PhD required with at least two years of laboratory experience
Minimum B.A./B.S. required with at least two years of laboratory experience
Experience Required: At least two years of wet bench laboratory experience
Cell culture
Western Blot
Cell viability assays
qPCR
DNA preparation (bacterial transformation, DNA extraction, transfection)
Lentivirus production
Mouse handling-tumor cell injections, mouse surgeries, IVIS imaging
Flow cytometry
Organoid development and culture
Microscopy
Lab record keeping
Contribute to laboratory maintenance

Preferred

Experience with mouse tumor models and related procedures (handling, tumor cell injection, flow cytometry, mouse surgical procedures, IVIS imaging) strongly preferred

Company

Mount Sinai Health System

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Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.

H1B Sponsorship

Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)

Funding

Current Stage
Late Stage
Total Funding
$41.9M
Key Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M

Leadership Team

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Vincent Tammaro
Executive Vice President and Chief Financial Officer
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David Feinberg
Senior Vice President, Chief Marketing and Communications Officer
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Company data provided by crunchbase