Metaphore Biotechnologies · 18 hours ago
Director, Protein & Cell Sciences
Somerville, MA
Full-time
Onsite
Director/Executive
$183K/yr - $231K/yr
10+ years expMetaphore Biotechnologies is a generative AI drug design company focused on creating a new class of functional antibodies. The Director of Protein & Cell Sciences will lead a team responsible for high-throughput production and characterization of antibodies, ensuring the delivery of high-quality therapeutic proteins to support research activities.
BiotechnologyProduct ResearchTherapeutics
Responsibilities
Lead an engaged and entrepreneurial team of 4-5 scientists that contributes significantly to the advancement of the internal and partnered portfolio, develops novel platforms and techniques, and delivers well-characterized, high-quality development candidates
Establish, maintain, and communicate best practices for biochemistry and cell biology techniques including expression, production, purification, and analytical and functional characterization of antibodies and related therapeutic proteins
Ensure high quality data management including the use of electronic laboratory environments/LIMS for data storage and retrieval, to maximize the potential of AI/ML methods to deliver high-quality leads
Partner with research informatics and laboratory automation teams to identify and implement opportunities for improved workflows, more efficient protein production and characterization, and parallelized therapeutic discovery
Make highly impactful contributions to programs as a scientific leader and expert on protein therapeutics
Implement and manage outsourced protein production and characterization work with CROs that complements internal resourcing
Serve as a major interface with downstream CMC functions and external CDMOs to enable seamless progression of molecules into and through DC nomination, process development, and early manufacturing
Accountable for resourcing decisions for programs within the HTPP function
Partner with peers on the Biotherapeutics leadership team to manage resources, budgets, and operations
Recruit, mentor, and develop a high-performing HTPP unit
Foster a culture of collaboration, innovation, and accountability by partnering with other functions within the Biotherapeutics unit and across Metaphore
Partner with external collaborators, CROs, and technology providers to expand capabilities and accelerate timelines
As a member of the Biotherapeutics leadership team, facilitate group operations and strategic decisions, contribute to the development of the culture and people within the group, and contribute to broader company-wide strategic initiatives
Qualification
Required
PhD in Protein Biochemistry, Molecular and Cell Biology, Structural Biology, or a related discipline, or non-PhD with appropriate skills and experience
10+ years of experience in biologics drug discovery and development
Deep knowledge of antibody expression, purification, and characterization workflows, including the implementation of automation solutions to enable high-throughput protein production
Experience managing biologics CROs to expand protein production/characterization capabilities and capacity
Strong interpersonal and communication skills, with an established track record of leading and developing people and teams in a fast-paced, entrepreneurial biotech environment
Benefits
Healthcare coverage
Annual incentive program
Retirement benefits
A broad range of other benefits
Company
Metaphore Biotechnologies
Metaphore Biotechnologies is a firm that uses biomimicry and machine learning to unlock the revolutionary therapeutic.
11-50 employees
H1B Sponsorship
Metaphore Biotechnologies has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (4)
2023 (1)
Funding
Current Stage
Early StageTotal Funding
$50MKey Investors
Flagship Pioneering
2023-05-16Undisclosed· $50M
Leadership Team
Lovisa Afzelius
Co-founder & CEO
Daniel Acker
Cofounder & Chief Innovation Officer
Recent News
Seattle TechFlash
2025-04-09
Company data provided by crunchbase