Eli Lilly and Company · 2 hours ago
Senior Advisor/Director - Heart Failure Research
US, Boston MA
Full-time
Onsite
Senior Level, Lead/Staff, Director/Executive
$138K/yr - $224K/yr
5+ years expEli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana, focused on discovering and bringing life-changing medicines to those in need. The Senior Advisor/Director for Heart Failure Research will provide strategic leadership in drug discovery and clinical development programs, leading a team to advance therapeutic candidates for cardiometabolic diseases.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Provide strategic leadership and problem-solving for heart failure drug discovery and clinical development programs, from target identification through IND-enabling studies
Lead and advise on the design, execution, and interpretation of in vivo and in vitro pharmacology studies to assess the efficacy, pharmacokinetics (PK), pharmacodynamics (PD), and safety of therapeutic candidates, including cardiac functional and electrophysiologic endpoints
Identify robust animal models, cell-based assays, and translational approaches for heart failure (including HFpEF and HFrEF), pulmonary hypertension, atrial fibrillation and other cardiac diseases, using internal and external resources
Serve as a subject matter expert on disease area biology, pathology, current treatments and next generation approaches to therapeutics, and contribute to the scientific community and represent science at Lilly through publications and presentations
Provide input into portfolio strategy and help shape the long-term scientific roadmap for heart failure, pulmonary hypertension, and atrial fibrillation within CMR
Maintain awareness of scientific advances, new concepts, enabling technologies, and external competitive intelligence to ensure the company's research remains innovative
Champion innovation by launching new initiatives, driving cross-functional execution, and leading collaborative scientific programs across multiple areas
Capitalize on AI tools to streamline and accelerate scientific discoveries and communications
Lead, mentor, and develop a high-performing team of scientists (junior through senior levels) with a ‘team first’ mentality to discover and validate targets, elucidate mechanisms of action, and advance programs that expand and deliver the heart failure, pulmonary hypertension, and atrial fibrillation pipeline
Set clear priorities, drive decision-making, and align resources to deliver high-quality outcomes on timelines
Develop and maintain integrated project plans, proactively identify scientific and operational risks, and implement mitigation strategies
Communicate complex scientific concepts and program updates clearly and concisely to senior leadership and cross-functional governance teams
Enable efficient outsourcing and external execution through CROs and partners, ensuring scientific strength and delivery
Collaborate with cross-functional teams, including medicinal chemistry/genetic medicines/bioproducts, toxicology/ADME, bioinformatics, and regulatory affairs, to integrate data and drive program results
Represent the preclinical function in external engagements with key opinion leaders, scientific collaborators, and potential partners
Contribute to regulatory documentation and filings, including materials supporting IND submissions
Support business development activities through scientific diligence and evaluation of external opportunities for potential partnering or in-licensing
Qualification
Required
Ph.D. in cardiovascular biology, pharmacology, molecular/cellular biology, or a related scientific area
5+ years of industry experience in preclinical drug discovery and development, with a proven track record of advancing therapeutic programs
Deep expertise in heart failure pathophysiology, including a strong understanding of preclinical models, translational endpoints, and the therapeutic landscape
Preferred
Experience with cardiovascular electrophysiology, myocardial excitability/conduction, and cardiac bio-signal interpretation (preclinical and/or translational) preferred
Demonstrated people leadership, including mentoring, performance management, and talent development
Strong collaboration and influencing skills with internal customers, external vendors/partners, and cross-functional governance
Benefits
Company bonus
Company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
H1B Sponsorship
Eli Lilly and Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (514)
2024 (236)
2023 (167)
2022 (133)
2021 (57)
2020 (52)
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
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2026-01-25
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