AstraZeneca · 3 hours ago
Senior Director, Digital & Computational Pathology
Gaithersburg, MD
Full-time
Hybrid
Lead/Staff, Director/Executive
$229K/yr - $344K/yr
5+ years expAstraZeneca is a global biopharmaceutical company, and they are seeking a Senior Director for Digital and Computational Pathology. This role involves defining and leading the strategy for DPCP image analytics, focusing on building compliant and scalable solutions while collaborating with various teams to deliver impactful insights and market-ready offerings.
BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Set a multi-year vision that connects scientific roadmaps with commercial opportunity, defining DPCP pathways, value propositions, and portfolio alignment across therapy areas
Design and execute GTM strategies for DPCP solutions, including segmentation, and commercialization models
Translate discovery and translational advances (e.g., image-based biomarkers, spatial analytics) into validated offerings; align on clinical utility, evidence generation, and regulatory strategy with therapy area teams
Co-create customer narratives, market requirements, and adoption programs with Franchises; build field enablement materials, and define success metrics (penetration, utilization, outcomes impact)
Own product life cycle for digital pathology capabilities—concept, MVP, validation, launch, and scale—ensuring user-centric design, compliance, and measurable value
Lead enterprise-grade platform validation (WSI ingestion, storage/rendering, annotation, algorithm deployment, audit trails), ensuring security, interoperability, and performance at scale
Oversee validation of algorithms (classification, segmentation, cell phenotyping, spatial fusion) with robust MLOps, monitoring, and continuous improvement
Define evidence plans that demonstrate analytical validity, workflow efficiency, and economic value; partner on HEOR and real-world performance studies
Follow regulatory pathways (GxP/IVD considerations), quality systems, and readiness for image-based biomarkers and diagnostics; engage with regulators and standards bodies as needed
Structure strategic collaborations with scanner vendors, CROs, diagnostics partners, health systems, and technology providers; negotiate commercial terms and co-development agreements
Build scalable, compliant workflows from sample receipt through imaging, QC, analysis, reporting, and knowledge capture; optimize throughput, turnaround time, and cost
Develop training, sales tools, messaging, and playbooks; support customer pilots, proof-of-value programs, and post-launch adoption/expansion
Evangelize capabilities across AZ and with external stakeholders; communicate impact to senior leadership with clear metrics and narratives
Qualification
Required
PhD, MD, or equivalent experience in Pathology, Biomedical Engineering, Computer Science, Data Science, or related field
5+ years in digital pathology, computational imaging, or applied AI/ML in biopharma/healthcare; 5+ years leading multidisciplinary teams and product portfolios at senior level
Deep knowledge of histopathology workflows, multiplex imaging (IHC/IF, mIHC, IMC, spatial transcriptomics), WSI formats, and image analysis methods
Proven track record building and commercializing digital health or diagnostics solutions, including pricing, packaging, channel strategy, and launch execution
Experience with deep learning, classical image analysis, spatial statistics, model validation, MLOps, and deployment at scale
Experience with biomarker validation, analytical/clinical validation frameworks, GxP/IVD pathways, and regulatory interactions for image-based endpoints or diagnostic solutions
Ability to influence R&D and Commercial stakeholders, synthesize complex science into clear customer value, and drive alignment toward measurable outcomes
Preferred
Board-certified pathologist or significant experience collaborating in pathology departments
Experience with companion diagnostics, LDT/IVD commercialization, health system adoption, and payer engagement
Hands-on familiarity with scanners, LIS/LIMS, digital viewers, annotation tools, and AI toolchains
Experience implementing SOPs, QMS elements, CAP/CLIA interactions, and performance KPIs for imaging laboratories
Background in outcomes research and economic value demonstration for digital diagnostics
Benefits
Short-term incentive bonus opportunity
Equity-based long-term incentive program (salaried roles)
Retirement contribution (hourly roles)
Commission payment eligibility (sales roles)
Qualified retirement program [401(k) plan]
Paid vacation and holidays
Paid leaves
Health benefits including medical, prescription drug, dental, and vision coverage
Company
AstraZeneca
AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.
10001+ employees
H1B Sponsorship
AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (11)
Funding
Current Stage
Public CompanyTotal Funding
$5.26B2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B
Leadership Team
Pascal Soriot
Executive Director and Chief Executive Officer
Aradhana Sarin
Group CFO and Executive Director
Recent News
Essential Business
2026-01-24
2026-01-23
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