Alexion Pharmaceuticals, Inc. · 19 hours ago
Senior Scientist – Biologics AI Innovation
Waltham, Massachusetts, United States of America
Full-time
Onsite
Mid, Senior Level
$117K/yr - $175K/yr
2+ years expAlexion Pharmaceuticals, Inc. is seeking an experienced and visionary Senior Scientist to drive Biologics AI innovation at their US R&D centers. This pivotal leadership role will focus on integrating artificial intelligence with wet-lab discovery to advance biologics engineering and mentor junior scientists while collaborating across functions.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Lead and design AI strategies for biologics discovery and engineering, with a focus on AI–wet lab integration and accelerated translation of computational findings to experiments
Oversee and guide the development of innovative models, including protein language models, structure prediction models, de novo protein design, and multi-modal approaches combining sequence, structure, and biological activity data
Act as a scientific bridge and champion for cross-functional collaboration between AI scientists and wet-lab teams within the US, and in close alignment with global teams
Drive the generation, curation, and utilization of high-quality wet-lab data; provide actionable feedback to experimental teams for optimizing data production for ML applications
Evaluate, recommend, and implement emerging technologies, adopting best practices in data science, computational biology, and protein engineering to ensure world-class innovation and delivery
Mentor junior scientists and provide scientific leadership in biologics AI, fostering a collaborative, innovative, and high-performing team environment
Communicate progress, challenges, and strategy to stakeholders at all levels, contributing to strategic decision-making and representing the team in internal and external collaborations
Author scientific publications, contribute to intellectual property, and serve as an ambassador for AstraZeneca in the external scientific community through presentations and collaborations
Qualification
Required
Master and 2+ years experience or Phd and 0+ years of experience in mathematics, physics, computer science, statistics, bioinformatics, or a related discipline, with substantial academic or industry experience in the application of AI/ML to biological problems
Deep expertise and hands-on track record in developing and deploying machine learning and deep learning models for protein sequence and structure analysis, biologics design, or related fields
Demonstrated experience in leading initiatives that combine computational modeling with experimental biology, ideally in a therapeutics or biopharmaceutical setting
Strong programming and analytical skills, including proficiency with Python and major AI/ML frameworks such as TensorFlow, PyTorch, or JAX
Familiarity with large-scale data engineering, cloud computing, and FAIR data principles
Excellent communication and leadership skills, with proven success in cross-functional environments and multi-site collaborations
Demonstrable record of scientific innovation, as evidenced by publications, patents, or successful project delivery in biologics discovery or engineering
Preferred
Experience with structural informatics, structural biology, or structure-based rational design
Experience with molecular dynamic simulation and structure modeling
Experience with multi-modal learning, agentic AI, or the integration of heterogeneous biological data formats
Prior leadership, mentoring, or line management experience in industrial or academic R&D
Recognized presence in the external scientific community through publications, conference presentations, or collaborations
Benefits
Various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles.
Qualified retirement programs
Paid time off (i.e., vacation, holiday, and leaves)
Health, dental, and vision coverage in accordance with the terms of the applicable plans.
Company
Alexion Pharmaceuticals, Inc.
Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.
1001-5000 employees
H1B Sponsorship
Alexion Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (49)
2024 (57)
2023 (51)
2022 (29)
2021 (27)
2020 (17)
Funding
Current Stage
Public CompanyTotal Funding
$5.8M2020-12-12Acquired
1999-02-12Post Ipo Equity· $5.8M
1996-02-29IPO
Leadership Team
Frederic Chereau
SVP, Strategy and Business Development
Imran Shakur
Director, IRT and Technology Lead
Recent News
BioWorld Financial Watch
2026-01-17
bloomberglaw.com
2025-12-20
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