Humana · 20 hours ago
Principal AI Security Architect
United States
Full-time
Remote
Senior Level, Lead/Staff
$157K/yr - $215K/yr
8+ years expHumana Inc. is committed to putting health first and is seeking a Principal-level AI Security Architect to lead their enterprise AI/ML security architecture. This role involves defining the security strategy for AI adoption and collaborating with various teams to ensure safe and compliant AI solutions.
Health CareHealth InsuranceInsuranceVenture Capital
Responsibilities
Serve as primary AI Security SME for the Cyber Security organization
Serve as the AI Security SME for major enterprise projects, providing expert guidance on AI security architecture, policies, and standards
Develop, refine, and govern the AI Security Capability Framework across the enterprise
Establish reference architectures and guardrails for first‑party LLMs, Azure OpenAI, Microsoft/GitHub Copilot, and third‑party AI features in SaaS platforms, with standardized patterns for identity, access, data protection, and plugin safety
Integrate AI security controls and requirements into enterprise architecture patterns and overlays, ensuring secure-by-design principles are applied
Lead the evaluation, selection, and implementation of AI security tools, working collaboratively with internal stakeholders and external partners
Stay current with advancements in AI/ML security, threat landscapes, and emerging technologies; proactively adapt frameworks and controls accordingly
Stay ahead of evolving AI threats and recommend cutting-edge security solutions by conducting research and innovation
Converts AI risks into actionable controls, KPIs, and board‑level narratives; aligns to NIST AI RMF and enterprise frameworks
Participate in and support audits, compliance reviews, and incident response as it relates to AI systems
Partner to develop and enforce AI security policies, including compliance with emerging standards (e.g., NIST AI RMF, ISO/IEC 42001)
Perform AI threat modeling and risk assessments to identify, prioritize, and mitigate security risks related to AI/ML initiatives
Serve as the AI Security SME for major enterprise projects, providing expert guidance on AI security architecture, policies, and standards
Collaborate with enterprise architects, engineering, DevOps, and security teams to ensure alignment of AI security practices with organizational strategy and regulatory requirements
Partner with engineering teams to integrate security controls into AI/ML lifecycle (data collection, model training, deployment)
Embed security automation into AI CI/CD (dataset checks, SBOMs for models, vulnerability scans of AI pipelines, policy-as-code, release gates) and ensure continuous validation for drift, bias, and robustness
Mentor and provide technical guidance to security engineers and project teams regarding AI security best practices
Work closely with product, legal, and compliance teams to ensure responsible AI practices
Create playbooks for AI-specific incident response (e.g., model compromise, data exfil via prompts, malicious fine-tuning), conduct tabletop exercises, and lead post-incident forensics and hardening
Drive red-team/blue-team exercises for AI systems and coordinate independent architecture reviews across product lines
Qualification
Required
Bachelor's or Master's degree in Computer Science, Information Security, Engineering, or related field
8+ years of progressive experience in information security, with at least 3 years focused on AI/ML security
Deep expertise in AI/ML architectures, model security, AI threat modeling, and AI risk assessment methodologies
Proven experience in AI security tool evaluation, selection, and integration
Demonstrated understanding of enterprise security frameworks, secure software development lifecycle, and regulatory compliance requirements (e.g., HIPAA, GDPR)
Strong ability to communicate complex technical concepts to technical and non-technical stakeholders
Experience working in large-scale, regulated enterprise environments
Relevant security certifications (e.g., CISSP, CCSP, Certified AI Security Professional) preferred
Experience developing and delivering code using modern CI/CD delivery methodologies
Preferred
Experience with Azure ML, Azure OpenAI, Microsoft/GitHub Copilot security patterns; integration with Microsoft 365, Entra ID, Defender, Purview for data protection and governance
Familiarity with HIPAA/HITECH, FDA guidance for software/ML in medical contexts, and PHI de‑identification/anonymization techniques (k‑anonymity, differential privacy)
Completed independent architecture reviews and red‑team exercises for flagship AI features; closed priority findings within SLA
Contributor to AI security research, open-source tooling, or standards development; experience conducting or guiding AI red-team exercises
Benefits
Medical, dental and vision benefits
401(k) retirement savings plan
Time off (including paid time off, company and personal holidays, volunteer time off, paid parental and caregiver leave)
Short-term and long-term disability
Life insurance
Company
Humana
Humana is a health insurance provider for individuals, families, and businesses.
10001+ employees
H1B Sponsorship
Humana has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (282)
2024 (246)
2023 (284)
2022 (274)
2021 (212)
2020 (84)
Funding
Current Stage
Public CompanyTotal Funding
$13.07B2025-05-30Post Ipo Debt· $5B
2025-03-03Post Ipo Debt· $1.25B
2024-03-11Post Ipo Debt· $2.25B
Leadership Team
Jim Rechtin
CEO and President
Cynthia Zipperle
Vice President, Chief Accounting Officer and Controller
Recent News
2026-02-04
HealthCareIT News
2026-02-04
HealthCareIT News
2026-02-04
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