AstraZeneca · 5 hours ago
Senior Scientist, Cell Therapy
US - Gaithersburg - MD
Full-time
Onsite
Mid, Senior Level
2+ years expAstraZeneca is a leading pharmaceutical company seeking a highly-motivated and independent Senior Scientist with expertise in Cellular Therapy, Immunology, and Computational Biology. The role involves designing and conducting laboratory experiments, developing methodologies, and generating and interpreting scientific data to advance innovative Cell Therapy products.
BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Conducts routine drug discovery research experiments by applying the techniques of molecular and cellular biology, communicates the results to team members, and is involved in the interpretation of data
Conducts hands-on in vitro research and contributes to the plans and designs of in vitro and in vivo studies
Supports a team and works collaboratively in a matrix environment
Assesses and reports data, with little or no guidance, in a clear and concise manner, while developing an understanding of its implications within the overall context of drug discovery
Uses their knowledge of coding, data processing, and AI platforms/ machine learning to extract knowledge and insights from structured and unstructured data sources relevant to the development of new therapies
Provides technical instruction to the team and allocates administrative work where possible
Communicates and shares information between distinct projects within the bioscience function and across other functions as required
Ensures own work, and work of peers, is compliant with Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations
Qualification
Required
PhD in a relevant discipline (e.g. Biology, Immunology, Immuno-Oncology, Biomedical Engineering) with a minimum of 2 years of demonstrated experience in Computational Biology, Data Science, and/ or Computer Science
Extensive in vitro skillset with a well-developed understanding of molecular and cellular biology, immunological assays, and cell transfection/ transduction, and advanced cell culture techniques
Ability to design, execute, and troubleshoot experiments, and to review, analyse, and interpret results
Proficiency in Python and/or R
Expertise in -omics technologies, and ability to process large-scale biological datasets (e.g. single-cell/spatial transcriptomics, in-house proprietary data sources such as in vitro or in vivo data)
Understanding of AI and predictive modelling tools
Preferred
Experience with genome editing technologies (CRISPR/ Cas9, base-editing, transposons, etc.)
Hands-on experience in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, cytokine measurement, and multi-parameter flow cytometry
Basic experience developing cellular therapies including CAR-T/ CAR-NK, TCR-T, and/ or TIL therapies
Background in drug discovery and development in the pharmaceutical industry
Prior experience in UNIX-based systems and high-performance computing (e.g. SLURM) with applications to large-scale data analysis and management
Experience developing and implementing machine learning models
In vivo skillset including animal handling, mouse tumour models, standard routes of dosing and engraftment, and tissue processing
Company
AstraZeneca
AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.
10001+ employees
H1B Sponsorship
AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (11)
Funding
Current Stage
Public CompanyTotal Funding
$5.26B2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B
Leadership Team
Pascal Soriot
Executive Director and Chief Executive Officer
Aradhana Sarin
Group CFO and Executive Director
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