Broad Institute of MIT and Harvard · 13 hours ago
Computational Scientist I
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$88K/yr - $124K/yr
4+ years expThe Broad Institute of MIT & Harvard is seeking a highly motivated Computational Scientist to join the Xavier Lab to lead and direct data generation and analysis projects designed to determine the underlying factors contributing to health and disease. The role involves overseeing data generation and analysis across various collaborations and executing analyses of large multi-omic datasets to identify biological features relevant to human health.
BiotechnologyClinical TrialsLife Science
Responsibilities
Oversee data generation and data analysis across various internal and external collaborations. Includes working datasets such as single-cell RNA-Seq, single-cell ATAC-Seq, spatial transcriptomics, proteomics, metabolomics, and/or microbiome data
Demonstrate flexibility to execute tasks requiring various skill levels and learn new skills as needed
Perform analyses using current processes and identify, propose, and implement improvements to ensure output of high-quality datasets
Work with other team members and leadership to plan project requirements and timelines, shift priorities as needed, and efficiently execute project tasks
Identify and help solve methodological problems, including adjustments to experimental and computational protocols to ensure generation of high-quality datasets suited to answer core biological questions
Use single cell and spatial transcriptomic approaches to understand tissue organization and how they are altered in disease environments such as chronic inflammation
Use a systems medicine approach to understand inflammatory and other diseases
Develop novel methods to facilitate exploration of unstructured datasets
Write well-crafted, maintainable, scalable, and performant code
Lead and carry out projects with minimal supervision
Participate in writing papers and grant proposals
Present project progress during group meetings
Qualification
Required
Ph.D. in Computational Biology, Computer Science, Physics, Math, Statistics, or related quantitative fields
4 to 5 years of experience working on projects utilizing bioinformatics, data analysis and statistics
Excellent critical thinking, research, and analytical skills
Excellent communication and interpersonal skills and the ability to work with biologists, computational biologists, data scientists, and software engineers
Must be able to work independently as well as part of a team in a fast-paced, highly collaborative environment
Must have experience that demonstrates the ability to carry out a variety of tasks in parallel, recognize and solve problems effectively, and shift priorities rapidly
Scientific and numerical programming in Python or R and knowledge of Machine Learning methods
Well versed in Next Generation Sequencing pipelines (single-cell RNA-Seq, single-cell ATAC-Seq, etc.)
Benefits
Medical, dental, vision, life, and disability insurance
401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
Employee assistance program
Among other Broad benefits
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
Research & Development World
2026-01-22
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