Boehringer Ingelheim · 1 day ago
Senior Scientist, PKPD Modeler
Ridgefield, CT
Full-time
Onsite
Senior Level
$140K/yr - $222K/yrBoehringer Ingelheim is seeking a highly motivated Senior Scientist – Preclinical PK/PD Modeler to join the Preclinical PK/PD Modeling group in the global Drug Discovery Sciences (DDS) department. The successful candidate will design and implement PK/PD models to support drug discovery and collaborate with key stakeholders to enhance research capabilities.
BiotechnologyHealth CareMedicalPharmaceutical
No H1B
Responsibilities
Independently develops PK/PD and quantitative systems pharmacology models that enhance decision making for novel therapeutic target and candidate selections and inform translational research strategies for novel therapeutics across multiple therapeutic areas like Oncology, Immunology, Cardiometabolic Diseases and more
Uses modeling and simulation for early dose feasibility assessment, predict human PK and efficacious dose/dose regimen, and influences selection of first-in-human starting dose
Designs, analyzes and interprets quantitative pharmacology and in vitro, ex vivo and in vivo PK/PD studies and communicates results to teams and management
Leverages literature data or proposes new experiments to validate models or test model-generated hypotheses
Develops new methodologies, protocols or procedures that contribute to core group/research goals and reflect expert knowledge
Serves as PK/PD modeling representative on multiple cross-functional project teams
Effectively collaborates with scientists within and outside functional area (e.g. therapeutic area biologists, protein engineering scientists, Clinical Pharmacology & Pharmacometricians)
Demonstrates collaborative excellence in a highly matrixed work environment across global teams
Develops broad knowledge in field of expertise, including the ability to interpret current literature relevant to R&D projects, and visibility outside of functional area
Presents work at internal/external scientific meetings and publishes work in scientific journals
Qualification
Required
Ph.D. in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Quantitative fields such as applied mathematics, pharmacometrics, biomedical and chemical engineering or related discipline with proven track record of applying biomedical modeling and simulation approaches in academia or industry
Theoretical and practical knowledge of pharmacokinetics, PK/PD and quantitative systems pharmacology modeling
Experience using one or more commercially available modeling and simulation platforms (e.g. Phoenix/WinNonlin, NONMEM, MATLAB, SimBiology, R, Julia, etc.)
Experience and the ability to review relevant scientific literature
Ability to build effective working relationships and influence others both inside and outside department
Strong aptitude for sharing expertise with cross-functional and global teams
Ability to communicate effectively both orally and in writing in an interdisciplinary environment
Committed to professional development of self and others
Strong teamwork skills with independent working style, high level of initiative, reliability, and readiness to take on responsibility
Must be legally authorized to work in the United States without restriction
Must be willing to take a drug test and post-offer physical (if required)
Must be 18 years of age or older
Preferred
Experience in mechanism-based PK/PD modeling of therapeutic proteins
Experience with modeling techniques like writing ODEs to capture a biological/physiological system
Proficiency with PBPK (whole-body and minimal) modeling applied to biologics and/or other drug modalities
Experience with computational tools used for validation and verification of mechanism-based models (e.g. parameter estimation, sensitivity analysis, virtual population/patient simulations)
Benefits
Role specific variable or performance based bonus
Other compensation elements
Company
Boehringer Ingelheim
Boehringer Ingelheim is a group of pharmaceutical companies that focuses on prescription medicines and animal health. It is a sub-organization of Boehringer Ingelheim.
Founded in 1885Ingelheim Am Rhein, Rheinland-Pfalz, DEU
10001+ employees
Funding
Current Stage
Late StageLeadership Team
Christian Eckermann
Corp. SVP BioPharma Network
Clemens Twardy
Corporate Vice President, Head of Global Supply Chain and Lifecycle Management Animal Health
Recent News
BioWorld Financial Watch
2026-02-02
Mexico Business
2026-02-02
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