PureTech Health · 17 hours ago
Director, R&D Operations
Boston, MA
Full-time
Hybrid
Director/Executive
$220K/yr - $260K/yr
8+ years expPureTech Health is a company focused on translating novel therapeutic concepts into new drug candidates. The Director of Research and Development will lead multiple programs through all phases of preclinical development and collaborate with internal teams and external contractors to ensure successful project outcomes.
Biotechnology
Responsibilities
Manage multiple projects from early preclinical discovery concepts to Phase 1 ready therapeutic candidates
Draft short- and long-term project timelines with critical path activities that reach key developmental milestones
Working with senior team members to support management of the synthesis, characterization and formulation of new therapeutic compounds for preclinical and early clinical testing
Design and manage in vitro experiments to characterize the pharmacology of new therapeutic compounds including stability, metabolism, mechanism of action, and toxicity studies
Design studies in rodents and large animals to evaluate the pharmacokinetic, pharmacodynamic and toxicological properties of new therapeutic compounds
Identify suitable disease models and design robust animal studies to evaluate the efficacy of new therapeutic compounds for target indications
Analyze preclinical data from in vitro experiments and in vivo animal studies, interpret key findings, and adjust development efforts as needed
Maintain detailed project budgets and work with corporate accounting to onboard new vendors, issue purchase orders, pay invoices, and track project spending
Identify and manage contract research and development organizations to support all planned experiments and studies
Identify and engage academic, industry and clinical consultants to support all aspects of drug candidate research and development
Prepare presentations and give regular updates senior leadership that summarize progress, key findings, challenges, and planned/proposed activities
Partner closely with internal teams to support intellectual property generation and fundraising activities as needed
Qualification
Required
Ph.D. or Pharm.D. in a scientific or engineering discipline
Minimum of 8+ years of experience in pharmaceutical research and development, with at least 5 years in a leadership or management role
Proven track record in preclinical development of small molecule drugs from early discovery to successful IND submissions
Experience leading multidisciplinary scientific teams and managing complex preclinical R&D programs
Strong scientific acumen with a deep understanding of drug development processes for novel small molecule drug candidates
Strategic thinker with the ability to translate therapeutic concepts into developmental candidates
Problem solving skills with the ability to analyze a problem from multiple perspectives and then select the optimal decision
Exceptional leadership, communication, and project management skills
Demonstrated ability to work collaboratively across departments and with external partners
Knowledge of regulatory requirements and intellectual property considerations in pharmaceuticals
Entrepreneurial and self-motivated work style
Ability to work a hybrid in-office schedule
Preferred
Working knowledge of medicinal chemistry to guide the synthesis and characterization of new therapeutic compounds
Benefits
Bonus
Equity compensation
Company
PureTech Health
PureTech Health is a hub-and-spoke biotherapeutics company dedicated to giving life to science and transforming innovation into value.
51-200 employees
H1B Sponsorship
PureTech Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (2)
2022 (2)
2021 (4)
2020 (1)
Funding
Current Stage
Growth StageLeadership Team
Daphne Zohar
Founder & CEO
Bill Steinkrauss
Interim Chief Financial Officer
Recent News
2024-04-29
Sharecast.com
2024-04-29
2024-04-29
Company data provided by crunchbase