Treeline · 8 hours ago
Senior/Principal Scientist, Formulation Development
Watertown, Massachusetts, United States
Full-time
Onsite
Senior Level, Lead/Staff
$165K/yr - $182K/yr
3+ years expTreeline Biosciences is seeking a Senior/Principal Scientist in Formulation Development, responsible for supporting phase appropriate formulation development for preclinical and clinical use. This role involves collaboration with various departments and external partners to manage formulation development and manufacturing activities effectively.
BiotechnologyHealth CareLife ScienceMedicalPrecision Medicine
Responsibilities
Provide technical oversight for formulation development and GMP manufacturing
Collaborate with CMC, Medicinal Chemistry, DMPK, Quality, Regulatory, and Clinical supply groups to advance preformulation and formulation plans
Proactively manage objectives, timelines, milestones, and budgets for formulation development and manufacturing activities
Able to critically troubleshoot problems, determine underlying causes, and propose well thought out solutions within existing constraints
Develop strong, collaborative working relationships with external partners; critically assess progress and actively drive experimental workplans at external CDMOs
Maintain an understanding of current trends and emerging technologies in small molecule formulation development, including bioavailability enhancement
Effectively communicate project progress to internal management and external CDMO partners
Authors technical summaries/reports and participates in the authorship and maintenance of CMC regulatory filings
Qualification
Required
Ph.D. in pharmaceutical sciences or related discipline and a minimum of 3-6+ years of relevant pharmaceutical experience in process chemistry; or M.S. in pharmaceutical sciences or related discipline and a minimum of 10-13+ years of relevant pharmaceutical experience
Formulation development expertise across a broad range of dosage forms. Experience developing phase appropriate drug product development
Prior experience working in a virtual CMC development environment with external CDMO partners
Strong understanding of GMP requirements for drug product development
Experience in the preparation and review of regulatory filings (including INDs, IMPDs, or other regulatory dossiers)
Focused on collaboration. Building and maintaining good working relationships with internal and external stakeholders is essential. Strong communication skills, both written and oral
Ability to work in a fast-paced and dynamic corporate environment with changing priorities and meet time sensitive program deadlines
Willingness to travel to various meetings or client sites, domestically or internationally when necessary
Company
Treeline
Treeline (or Treeline Biosciences) is a privately held, clinical-stage biopharma company that aspires to make medicines at the highest level.
51-200 employees
H1B Sponsorship
Treeline has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (4)
2023 (3)
2021 (1)
Funding
Current Stage
Growth StageTotal Funding
$1.09BKey Investors
AI Life Sciences Investments LLCKohlberg Kravis RobertsARCH Venture Partners,Google Ventures,OrbiMed
2025-09-03Series A· $200M
2024-10-17Undisclosed· $421M
2022-10-11Series A· $261.27M
Leadership Team
Spencer Smith
Chief Financial Officer
Recent News
Boston Globe
2026-01-16
2025-10-04
Company data provided by crunchbase