Thymmune Therapeutics · 9 hours ago
Research Associate/ Senior Research Associate, In Vivo
Thymmune Therapeutics is a preclinical biotechnology company based in Cambridge, MA, focusing on immune cell therapy products. The Research Associate/Senior Research Associate role involves conducting in vivo studies and pharmacology, as well as collaborating across teams to analyze data and mentor junior staff.
BiotechnologyTherapeutics
Responsibilities
Execute in vivo studies using mouse models, including dosing, monitoring, and tissue collection at necropsy
Perform standard dosing and sampling techniques, including SC, IM, IV (retro-orbital), and IP injections, as well as submandibular bleeds and tail nick
Conduct or assist with small rodent surgical procedures (e.g., tissue transplantation/implantation); experience in this area is a key asset
Perform specialized tissue processing and imaging techniques, including immunohistochemistry (IHC) and immunofluorescence (IF) staining
Assess in vivo functionality, safety, and tumorigenicity of stem cell-derived cell product
Maintain and expand primary cell cultures using aseptic technique
Perform cell isolation from primary human or mouse tissues for downstream analysis
Conduct downstream biological assays to validate cell quality and function, including Flow Cytometry (FACS), RT-qPCR, and ddPCR, MSD/ELISA
Analyze biomarkers and signalling pathways to correlate in vitro characteristics with in vivo outcomes
Analyze complex datasets using statistical software (e.g., GraphPad Prism) and present findings to the scientific team
Maintain high standards of data integrity and ensure accurate documentation for research reports and study protocols
Contribute to the writing of study reports and participate in the strategic planning of long-term studies
Collaborate with cross-functional teams, support junior laboratory staff and interns, fostering a collaborative working environment
Qualification
Required
Education: B.S. or M.S. in Cell Biology, Immunology, Regenerative Medicine, or a related discipline
Experience: 3–5+ years of relevant industry experience (Biotech/Pharma experience preferred)
In Vivo Skills: Proficiency in rodent handling, multiple routes of administration (IV, IP, SC), and tissue dissection is required
Analytical Skills: Strong experience with Flow Cytometry, qPCR, and microscopy. Ability to analyze data statistically and troubleshoot experimental variances independently
Other Skills: Excellent oral and written communication skills. Must be able to structure tasks, set priorities, and work effectively in a collaborative, team-oriented environment
Preferred
In Vitro Skills: Hands-on experience with the isolation and culture of primary human cells or tissues is preferred
Company
Thymmune Therapeutics
Thymmune Therapeutics is a biotechnology company developing a machine learning-driven thymic cell engineering platform.
H1B Sponsorship
Thymmune Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2022 (1)
Funding
Current Stage
Early StageTotal Funding
$44MKey Investors
Advanced Research Projects Agency for HealthPillar VC
2023-09-29Grant· $37M
2023-03-01Seed· $7M
Recent News
2025-05-04
Google Patent
2025-02-09
Google Patent
2025-02-09
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