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Senior Principal Operational Scientist – Aging & Metabolism jobs in United States
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Johnson & Johnson · 20 hours ago

Senior Principal Operational Scientist – Aging & Metabolism

Johnson & Johnson is a leader in healthcare innovation, committed to building a world where complex diseases are effectively managed. The Senior Principal Operational Scientist will provide scientific leadership and operational support for translational research in thrombosis, sarcopenia, and cardiometabolic diseases, integrating scientific responsibilities with project management and coordination tasks.
Hospital & Health Care
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Lead and provide expertise in in vitro and in vivo studies supporting cardiometabolic and cardiopulmonary research
Contribute to target identification, validation, and preclinical strategy development in areas such as HFpEF, Group 2 PH, vascular dysfunction, thrombosis, and age‑related muscle loss and weakness
Partner with disease area leaders and project teams to develop mechanistic hypotheses and experimental plans aligned with Cardiopulmonary priorities
Uphold strong scientific standards through rigorous data interpretation, clear internal communication, and contributions to publications and presentations
Support project management for aging‑focused cardiopulmonary programs, ensuring clear milestones, timelines, and decision points
Prepare and maintain project documentation, including development plans, data packages, governance materials, and decision‑support documents
Organize and support internal and external meetings by preparing agendas, documenting outcomes, and ensuring timely follow‑up on action items

Qualification

Muscle biologyCardiovascular researchMetabolismProject managementCross-functional collaborationCommunication skills

Required

Bachelor's degree is required
Minimum of 8-10 years' experience working in muscle biology, cardiovascular, and metabolism in the Pharmaceutical/Biotechnology industry (which can include education)
Strong scientific background in biology (e.g., aging, metabolism, cardiopulmonary, muscle biology) or in chemistry/biologics
Experience contributing scientifically to drug discovery or translational programs in cardiometabolic, cardiovascular, or muscle‑related disease
Demonstrated experience working in cross‑functional, matrixed research teams
Strong written and verbal communication skills and the ability to manage multiple priorities effectively
Travel up to 10% of the time (domestic and international), defined by business needs

Preferred

Master's degree or PhD is highly preferred

Benefits

Medical
Dental
Vision
Life insurance
Short and long-term disability
Business accident insurance
Group legal insurance
Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation –120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
Holiday pay, including Floating Holidays –13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period 10 days
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year

Company

Johnson & Johnson

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At Johnson & Johnson, we believe health is everything.

H1B Sponsorship

Johnson & Johnson has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (48)
2024 (56)
2023 (58)
2022 (59)
2021 (44)
2020 (27)

Funding

Current Stage
Late Stage

Leadership Team

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Alex Gorsky
Former Chairman and CEO, Johnson & Johnson
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Joaquin Duato
Chairman of the Board and Chief Executive Officer
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Company data provided by crunchbase