Johnson & Johnson Innovative Medicine · 4 hours ago
Senior Principal Operational Scientist – Aging & Metabolism
Spring House, PA
Full-time
Hybrid
Senior Level, Lead/Staff
$137K/yr - $236K/yr
8+ years expJohnson & Johnson Innovative Medicine is dedicated to healthcare innovation and building solutions for complex diseases. They are seeking a Senior Principal Operational Scientist to provide scientific leadership and operational support for translational research in thrombosis, sarcopenia, and cardiometabolic diseases.
Pharmaceuticals
Responsibilities
Lead and provide expertise in in vitro and in vivo studies supporting cardiometabolic and cardiopulmonary research
Contribute to target identification, validation, and preclinical strategy development in areas such as HFpEF, Group 2 PH, vascular dysfunction, thrombosis, and age‑related muscle loss and weakness
Partner with disease area leaders and project teams to develop mechanistic hypotheses and experimental plans aligned with Cardiopulmonary priorities
Uphold strong scientific standards through rigorous data interpretation, clear internal communication, and contributions to publications and presentations
Support project management for aging‑focused cardiopulmonary programs, ensuring clear milestones, timelines, and decision points
Prepare and maintain project documentation, including development plans, data packages, governance materials, and decision‑support documents
Organize and support internal and external meetings by preparing agendas, documenting outcomes, and ensuring timely follow‑up on action items
Qualification
Required
Bachelor's degree is required
Minimum of 8-10 years' experience working in muscle biology, cardiovascular, and metabolism in the Pharmaceutical/Biotechnology industry (which can include education)
Strong scientific background in biology (e.g., aging, metabolism, cardiopulmonary, muscle biology) or in chemistry/biologics
Experience contributing scientifically to drug discovery or translational programs in cardiometabolic, cardiovascular, or muscle‑related disease
Demonstrated experience working in cross‑functional, matrixed research teams
Strong written and verbal communication skills and the ability to manage multiple priorities effectively
Travel up to 10% of the time (domestic and international), defined by business needs
Preferred
Master's degree or PhD is highly preferred
Benefits
Medical
Dental
Vision
Life insurance
Short and long-term disability
Business accident insurance
Group legal insurance
Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation –120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
Holiday pay, including Floating Holidays –13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period10 days
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year
Company
Johnson & Johnson Innovative Medicine
Johnson and Johnson Innovative Medicine focuses on developing medical solutions for some of the challenging diseases and medical conditions.
10001+ employees
Funding
Current Stage
Late StageLeadership Team
Molly Perkins
VP, Head of Cell & Genetic Medicines Discovery
Recent News
2025-08-14
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