Revolution Medicines · 15 hours ago
Scientist II, Process Chemistry
Redwood City, California, United States
Full-time
Hybrid
Mid, Senior Level
$132K/yr - $166K/yr
2+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Scientist II, Process Chemistry will be responsible for research, development, and technology transfer of chemical processes to commercial scale, with direct laboratory responsibilities.
Health CareLife ScienceMedical
Responsibilities
Develop chemical processes through design and execution of laboratory experiments. Design and propose viable alternative chemistry for drug substance and intermediates, including route evaluation and process optimization
Analyze and interpret experimental data to troubleshoot reactions, identify anomalies, and improve operational efficiency, yield, and purity of synthetic procedures
Independently perform multi-step organic syntheses, including the purification, and characterization of intermediates and final compounds
Maintain a detailed, accurate and up-to-date electronic notebook. Author process development reports as need to support knowledge capture. Present experimental findings and recommendations in team meetings
Partner with analytical development, pharmaceutical development, and supply chain functions to maintain overall project timelines
Author detailed experimental procedures, and technical reports to support regulatory filings and internal documentation
Collaborate with internal and external teams to ensure smooth technology transfer and process implementation at external partners
International travel to CRO/CDMO for the oversight of development activities and manufacturing (up to approximately 10%)
Qualification
Required
PhD in organic chemistry or a related discipline and a minimum of 2-5 years of related experience (may include post-doc); MSc degree in organic chemistry or a related discipline with 8+ years of relevant experience, or a BS degree in chemistry and a minimum of 10+ years of experience in chemical experimentation
Hands-on experience with detailed reaction analysis in synthetic organic chemistry
Impurity identification with structural elucidation through NMR, HPLC, and LC-MS for routine analysis is essential
Written and verbal communication to enable effective and efficient discussions of detailed and complex scientific ideas, results, and procedures
Functional data plotting to identify trends and dependencies is a must
High competence with the Microsoft and ChemDraw suites to communicate research results in a compelling manner is expected
Preferred
A gifted experimentalist with deep mechanistic curiosity and an ability to push arrows
An open communicator, eager to brainstorm and discuss ideas and experiments
A scientist who appreciates the beauty of a well-designed, properly executed experiment
A curious person who isn't afraid to be wrong and learn from their mistakes
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
Genetic Engineering News
2026-02-02
Pharmaceutical Technology
2026-01-13
Company data provided by crunchbase