Hexagon Bio · 10 hours ago
Scientist II / Senior Scientist, Protein Science: Antibody / ADC Analytics and Engineering
Menlo Park, CA
Full-time
Onsite
Mid, Senior Level
$140K/yr - $180K/yr
3+ years expHexagon Bio leverages a genomics-based platform to develop next-generation medicines for human disease. The Scientist in the Protein Science group will contribute to the advancement of therapeutic interventions by developing and characterizing antibody drug conjugates (ADCs) and collaborating with cross-functional teams.
BiotechnologyHealth CareTherapeutics
Responsibilities
Drive analytical efforts supporting the development of novel therapeutic ADCs
Drive antibody production and protein engineering efforts
Perform antibody and ADC characterization and developability assessments using a variety of biophysical and biochemical analytical methods
Drive in vivo study workflows with in-use stability testing and dose formulation analyses
Work closely with biologists and medicinal chemists to advance antibody drug conjugates from discovery through to development
Analyze and interpret data, and effectively communicate findings to multi-disciplinary teams
Qualification
Required
PhD in Biochemistry, Bioengineering, Biophysics, Structural Biology, or related disciplines with at least 3-5 years of experience in the biotech and/or pharma industry
Extensive hands-on experience with therapeutic antibody characterization and early development
Demonstrated expertise with analytical approaches for antibody characterization including HPLC-SEC / HIC / RP, large molecule intact mass spec, capillary electrophoresis, nanoDSF and binding (BLI/SPR/ELISA). Similar analytical experience with ADCs is desirable
Hands-on laboratory experience in antibody production workflows including expression and purification (i.e. AKTA: Affinity / IEX / HIC / SEC), and QC
Experience with antibody engineering workflows including optimization of molecule properties
Ability to tackle complex scientific problems in a cross-functional environment
Effective communication and ability to coordinate tasks across multiple projects as part of a multidisciplinary research team
Proven ability to support and enable team members
Initiative and boldness to dive into a fast-paced new startup
Preferred
Experience working with Contract Development Manufacturing Organizations (CDMOs) including assay qualification / validation and report generation
Benefits
A comprehensive suite of medical, dental, and vision insurance plans through TriNet, which offers additional voluntary benefits (pet insurance, accident insurance, home & auto insurance, and more)
Equity and a 401(k) plan
Access to scientific conferences all over the country throughout the year
A range of amenities, courtesy of the Menlo Park Labs business park, including shuttle, gym, rock-climbing wall, pool, sports courts, cafe, bike lockers, and free EV charging stations
Opportunities to engage with the Hexagon community through team-building events like our Hexagon Happy Hours and holiday parties
Company
Hexagon Bio
Hexagon Bio is a data-driven biotech company developing targeted small molecule therapeutics.
51-200 employees
H1B Sponsorship
Hexagon Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (4)
2022 (1)
Funding
Current Stage
Growth StageTotal Funding
$193.6MKey Investors
Nextech InvestThe Column Group8VC
2022-10-11Series B· $77.3M
2021-09-22Series Unknown· $61M
2020-09-15Series A· $47M
Leadership Team
Maureen Hillenmeyer
Founder and CEO
Recent News
2026-02-03
2025-12-19
2025-12-16
Company data provided by crunchbase