Praxis Precision Medicines, Inc. · 14 hours ago
Manager or Sr. Manager, Clinical Supply Chain
United States
Full-time
Remote
Senior Level
$115K/yr - $155K/yr
5+ years expPraxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for central nervous system disorders. They are seeking a knowledgeable Manager or Senior Manager of Clinical Supply Chain to ensure clinical trials are ready to run without delay, overseeing planning, execution, and compliance throughout the study lifecycle.
Alternative MedicineBiotechnologyHealth CareMedicalPrecision Medicine
Responsibilities
Supply strategy development for assigned clinical programs or studies, including forecasting and demand planning as well as packaging, labeling, and distribution oversight
Depot and site supply management
Returns, reconciliation, and destruction
Develop and maintain integrated supply plans aligned with protocol requirements and study timelines
Support study startup activities, including IRT design input, pharmacy manual development, and vendor onboarding
Monitor supply performance throughout study execution and proactively resolve issues related to supply shortages, excursions, and distribution challenges
Manage relationships with clinical supply vendors (e.g., depots, packaging/labeling vendors, couriers, IRT providers)
Lead vendor forecasting discussions, review performance metrics, and manage issue resolution
Author, review, and approve clinical supply-related documents, including pharmacy manuals, supply plans, shipping documentation, vendor specifications and work orders
Ensure all activities are conducted in compliance with GxP requirements, internal SOPs, and applicable regulations
Support inspection readiness activities and participate in audits and inspections as needed
Identify clinical supply risks and implement mitigation strategies to protect study timelines and patient safety
Support quality events, deviations, CAPAs, and change management activities
Qualification
Required
Bachelor's degree in a scientific, clinical, or supply chain–related discipline (or equivalent experience) with a minimum of 5 to 8 years of experience in Clinical Supply management in a pharmaceutical or biotechnology environment – small or mid-sized biotech environment preferred
Demonstrated experience managing end-to-end clinical supply activities for clinical trials
Proven ability to independently manage multiple studies simultaneously
Strong working knowledge of GxP requirements and clinical trial operations
Strong organizational and project management skills
Proactive problem-solving and risk-based decision-making
Ability to operate independently with minimal supervision
Effective cross-functional communication and stakeholder management
Comfort operating in a fast-paced, evolving environment
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus
Preferred
Experience supporting Phase 2 and/or Phase 3 clinical trials strongly preferred
Preferred hands-on experience with DTP/DFP models, IRT systems, and global clinical supply distribution
Preferred experience supporting audits and regulatory inspections
Benefits
99% of the premium paid for medical, dental and vision plans.
Company-paid life insurance
AD&D
Disability benefits
Voluntary plans to personalize your coverage.
We match dollar-for-dollar up to 6% on eligible 401(k) contributions
Long-term stock incentives
ESPP.
Discretionary quarterly bonus
Flexible wellness benefit
Generous PTO
Paid holidays
Company-wide shutdowns.
Company
Praxis Precision Medicines, Inc.
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.
51-200 employees
Funding
Current Stage
Public CompanyTotal Funding
$1.67BKey Investors
Eventide
2026-01-06Post Ipo Equity· $575M
2025-10-16Post Ipo Equity· $525M
2024-03-28Post Ipo Equity· $200M
Leadership Team
Marcio Souza
President and CEO
Tim Kelly
Chief Financial Officer
Recent News
Clinical Trials Arena
2026-02-03
Company data provided by crunchbase