NewLimit · 11 hours ago
Senior Research Associate, Metabolism
South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$90K/yr - $105K/yr
2+ years expNewLimit is a biotechnology company working to radically extend human healthspan. They are seeking a Senior Research Associate with experience in liver biology or in vivo physiology to join their Metabolism team, focusing on developing reprogramming medicines to restore youthful function in aged hepatocytes in the context of metabolic disease.
BiotechnologyClinical TrialsHealth Care
Responsibilities
Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test epigenetic reprogramming interventions for aged and diseased hepatocytes
Perform experiments in preclinical animal models of liver disease
Conduct functional and phenotypic assays to evaluate the effects of reprogramming on hepatocyte biology in vivo
Deliver epigenetic reprogramming perturbations to hepatocytes in vivo using multiple transgenic manipulation methods (e.g. viral vectors, lipid nanoparticles)
Isolate murine and human hepatocytes by liver perfusion with downstream FACS analysis
Qualification
Required
BS in cell biology, molecular biology, or a related natural science and 2+ years of work experience in a cell biology or animal physiology laboratory (academic or industry setting)
Proficiency in animal handling and husbandry techniques for rodent models (mice or rats)
Exceptional organizational skills, including detailed experimental record-keeping and the ability to manage multiple concurrent projects
Experience with standard molecular biology techniques, including gel electrophoresis, nucleic acid purification, and PCR
Preferred
Experience working with mouse models of aging, disease and liver dysfunction
Experience with in vivo manipulation of hepatocytes and liver perfusion techniques
Experience with single-cell genomics or other functional genomics approaches
Proficiency in molecular biology and molecular cloning methods
Benefits
Health, dental, and vision insurance
401(k) with company match
Paid parental leave
Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays
Meals and snacks on-site
Company
NewLimit
NewLimit is a biotech company developing epigenetic therapies to extend human healthspan by reprogramming aging cells.
11-50 employees
H1B Sponsorship
NewLimit has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (2)
Funding
Current Stage
Growth StageTotal Funding
$247.25MKey Investors
Kleiner Perkins
2025-10-20Convertible Note· $45M
2025-05-06Series B· $130M
2023-05-16Series A· $72.25M
Leadership Team
Blake Byers
Co-Founder
Recent News
Longevity.Technology - Latest News, Opinions, Analysis and Research
2025-11-28
2025-11-17
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