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Antibody and Protein Engineering Platform Head jobs in United States
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Innovent Biologics · 1 day ago

Antibody and Protein Engineering Platform Head

Innovent Biologics is a company focused on advancing antibody and protein engineering. They are seeking a Platform Head to lead antibody discovery processes, guide engineering modifications, and collaborate with cross-functional teams to optimize R&D efforts.
BiopharmaBiotechnologyManufacturing
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H1B Sponsor Likelynote
Hiring Manager
Chao Pan 潘超
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Responsibilities

Proficient in the full process of antibody discovery, guiding antibody screening platforms (e.g., hybridoma, single B-cell, display platforms) for antibody selection
Responsible for antibody and protein engineering modifications, including humanization, affinity maturation, de-immunization, stability optimization, Fc engineering, and cytokine modifications
Lead the design and molecular optimization of bispecific and multispecific antibody formats, ensuring expression levels, developability, immunogenicity, and pharmacokinetic properties meet downstream development requirements
Conduct high-throughput expression of antibodies and proteins, along with early-stage developability testing and physicochemical characterization
Collaborate closely with cross-functional teams (e.g., functional biology, pharmacology) to advance project progress
Provide strategic recommendations at internal project reviews and leadership meetings
Track cutting-edge technologies (e.g., AI-assisted antibody discovery, novel antibody development) to continuously optimize and upgrade the R&D platform

Qualification

Antibody development techniquesProtein engineeringMolecular cloningProtein expressionPurificationEnglishTeam managementLeadership abilitiesAdaptabilityProblem-solving skills

Required

Ph.D. in Molecular Biology, Structural Biology, Genetic Engineering, Bioengineering, Biopharmaceuticals, or related fields
Expertise in antibody development techniques, including hybridoma, phage/yeast display, molecular cloning, protein expression and purification, and affinity maturation, with a focus on antibody engineering
Minimum 10 years of industrial R&D experience in antibody discovery or protein engineering, with a preference for candidates who have successfully led projects to PCC and clinical stages
Experience in managing teams of 30+ members, with strong adaptability and problem-solving skills in high-pressure, fast-changing environments
Proficiency in antibody and protein structural analysis, with hands-on experience in designing and optimizing bispecific and multispecific antibodies
Deep understanding of antibody structure-function relationships, sequence optimization, and expression/purification workflows
Familiarity with antibody developability and immunogenicity assessment, Fc engineering, and half-life extension strategies
Excellent research capabilities, demonstrated by patents or scientific achievements
Proficiency in English as a working language
Strong team management and leadership abilities
Ability to adapt quickly and handle complex tasks under pressure and rapid changes

Preferred

Overseas background, especially experience in multinational pharmaceutical companies

Company

Innovent Biologics

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Innovent Biologics is a biopharmaceutical company that develops and manufactures monoclonal antibodies.

H1B Sponsorship

Innovent Biologics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (1)
2022 (2)
2021 (2)

Funding

Current Stage
Public Company
Total Funding
$1.52B
Key Investors
TakedaSanofiCapital Group Private Markets
2025-10-21Post Ipo Equity· $100M
2025-06-26Post Ipo Equity· $547.83M
2022-08-04Post Ipo Equity· $308.29M

Leadership Team

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Qinwei Zhou
COO
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Ronald Ede
Executive Director of the Board
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Company data provided by crunchbase