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Staff Infrastructure Engineer jobs in United States
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Kalderos · 14 hours ago

Staff Infrastructure Engineer

Kalderos is dedicated to building technologies that enhance transparency and equity in the healthcare sector, particularly in pharmaceutical pricing. They are seeking a Staff Infrastructure Engineer to own critical infrastructure, lead complex initiatives, and improve reliability and security across their platform.
Health CarePharmaceuticalSaaS
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H1B Sponsor Likelynote

Responsibilities

Define and evolve infrastructure and support platform architecture for key products and services
Drive a multi-year roadmap for reliability, security and support platform capabilities
Establish reference architectures and golden paths that product and data teams can adopt
Lead adoption of SRE practices: SLOs/SLIs, error budgets, incident management, and post-incident reviews
Design and maintain observability (metrics, logs, traces, alerts, dashboards) across services and infrastructure
Automate runbooks and self-healing mechanisms to reduce toil and improve MTTR
Design and evolve a self-service platform (environments, CI/CD, infra templates) that helps teams ship safely and quickly
Own and improve Infrastructure as Code (IaC) and GitOps workflows
Build reusable platform components and tools that standardize how services are built, deployed, and operated
Partner with Security and Compliance to embed zero-trust, least privilege, and encryption into infrastructure patterns
Support healthcare-grade compliance (e.g., SOC 2, HIPAA, HITRUST) through infrastructure design and automation
Collaborate with data teams on secure, reliable data platforms and pipelines
Lead FinOps practices: visibility into spend, cost optimization, and guardrails that balance cost and reliability
Design for resilience and recovery: backup/restore, DR, and regional failover strategies
Continuously tune performance and capacity across compute, storage, and networking

Qualification

Cloud architectureInfrastructure as CodeKubernetesCI/CD pipelinesSRE principlesCloud securityData platformsMentoringCommunication skillsCollaboration

Required

Deep experience with at least one major cloud provider, Azure preferred, (AWS, Azure, or GCP) at an architectural level; proven ability to design and operate highly available, secure, cloud-native systems
Hands-on experience with Kubernetes or similar, plus key ecosystem tools (ingress, service mesh, operators)
Expert with IaC (Terraform, CloudFormation, Pulumi, etc.), modular design, and automation using Python, Go, or similar
Experience designing and maintaining CI/CD pipelines (e.g., GitHub Actions, GitLab CI, CircleCI, Azure DevOps), including progressive delivery (blue/green, canary, feature flags) and safe rollback
Strong understanding of SRE principles and hands-on work with observability stacks (e.g., Prometheus, Grafana, OpenTelemetry, ELK/EFK, Datadog, New Relic)
Deep understanding of cloud security best practices, IAM, network segmentation, secrets management, and encryption; familiarity with frameworks like SOC 2, HIPAA, HITRUST; strong grasp of networking (VPCs, subnets, routing, load balancers, VPNs, firewalls)
Experience supporting data platforms and pipelines in the cloud and familiarity with ML/AI infrastructure impacts on architecture and cost
Demonstrated ability to set technical direction and influence multiple teams without formal authority
Proven track record leading complex, cross-functional initiatives from design through rollout
Strong written and verbal communication skills; able to explain tradeoffs and decisions to both engineers and business stakeholders
Passion for mentoring and coaching other engineers and raising the overall technical bar
Comfort operating in ambiguity, making pragmatic decisions, and iterating as you learn

Preferred

Experience in healthcare, pharma, or other highly regulated industries
Familiarity with payment systems, EDI, or large-scale data integrations
Familiarity with file transfer mechanism such as SFTP, AS2 etc
Prior experience building or evolving internal platforms / platform engineering teams
Experience in high-growth or rapidly changing environments where infrastructure had to adapt quickly

Benefits

Medical, Dental, and Vision benefits
401k with company match
Flexible PTO with a 10 day minimum
Mobile & Wifi Reimbursement
Commuter Reimbursement
Donation matching for charitable contributions
Travel reimbursement for healthcare services not available near your home
New employee home office setup reimbursement

Company

Kalderos

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Kalderos provides a SaaS based drug discount management solution, which identifies, checks, and resolves non-compliance.

H1B Sponsorship

Kalderos has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (4)
2023 (1)
2022 (1)
2021 (8)
2020 (4)

Funding

Current Stage
Growth Stage
Total Funding
$76.28M
Key Investors
Bain Capital VenturesMercato Partners
2025-01-03Series Unknown· $26.35M
2022-09-09Series Unknown· $14.93M
2020-06-15Series B· $28M

Leadership Team

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Angie Franks
Chief Executive Officer
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James William Schuyler
Co-Founder
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Company data provided by crunchbase