Thermo Fisher Scientific · 1 day ago
Senior Scientist – LNP Formulation
Boston, MA
Full-time
Onsite
Mid, Senior Level
$95K/yr - $105K/yr
2+ years expThermo Fisher Scientific is a leading global contract research organization dedicated to making the world healthier, cleaner, and safer. The Senior Scientist – LNP Formulation will be responsible for manufacturing and optimizing LNP formulations, troubleshooting processes, and maintaining thorough documentation while working collaboratively within a team.
BioinformaticsBiotechnologyCloud Data ServicesConsultingHealth CareLife ScienceManagement Information SystemsOffice SuppliesPrecision Medicine
No H1B
Responsibilities
Manufacture small and large scale LNP formulations including production, purification and analysis of LNPs using industry standard protocols
Meet established deadlines
Maintain clear and complete ELN-based experimental records
Take part in troubleshooting arise during protocol execution and identify opportunities for protocol and/or process improvement
Support LNP optimization and formulation processes development such as mixing rate and purification conditions to improve yields and scalability of formulation
Troubleshoot low-yield processes and compositions to achieve formulation targets (i.e., composition design to enable specific delivery outcomes)
Follow SOPs to generate and maintain thorough and accurate documentation
Proven ability to adapt to strategic changes in a dynamic and fast-paced drug development environment
Willingness to learn new techniques and expand technical capabilities
Ability to work collaboratively within a team
Qualification
Required
Must be legally authorized to work in the United States without sponsorship
Must be able to pass a comprehensive background check, which includes a drug screening
Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years')
OR Masters degree
Extensive hands-on experience in various LNP formation mixing technologies, including but not limited to various microfluidic mixing and Impingement Jet Mixing devices
Ample hands-on experience and knowledge on LNP purification techniques including TFF
Proficiency in assembling and operating various mixer and TFF systems
Deep hands-on experience in LNP process development experiments focused on maintaining product quality
Experience on LNP formulation manufacturing for non-human primate studies
Complete knowledge and experience on various LNP analytics including Size, PDI, RNA encapsulation, Osmolality, and Endotoxin measurement
Exemplary work ethic and commitment to scientific rigor
Strong communication skills
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner
Able to work upright and stationary and/or standing for typical working hours
Able to lift and move objects up to 25 pounds
Able to work in non-traditional work environments
Able to use and learn standard office equipment and technology with proficiency
May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities
Benefits
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
Company
Thermo Fisher Scientific
Thermo Fisher Scientific is a biotechnology and laboratory equipment company that provides a wide range of scientific products and services.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$15.97BKey Investors
National Grid
2025-11-24Post Ipo Debt· $2.42B
2025-09-30Post Ipo Debt· $2.5B
2023-08-07Post Ipo Debt· $2.95B
Leadership Team
Stephen Williamson
Senior Vice President and Chief Financial Officer
Michel Lagarde
Chief Operating Officer
Recent News
Boston Herald
2026-02-07
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