Parabilis Medicines · 16 hours ago
Senior Director, Clinical Sciences
United States
Full-time
Remote
Director/Executive
$265K/yr - $305K/yr
10+ years expParabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for diseases with urgent unmet needs. The Senior Director, Clinical Sciences will provide scientific and strategic leadership across clinical development programs, ensuring scientific rigor and regulatory alignment.
Biotechnology
Responsibilities
Lead and own clinical science strategy for one or more clinical programs across development stages
Drive scientific input into protocol design, endpoint selection, and clinical development plans
Serve as a core contributor to regulatory interactions, governance decisions, and program reviews
Influence portfolio strategy through integrated clinical and translational insights
Partner closely with Clinical Operations to ensure scientifically sound and feasible trial execution
Interpret and contextualize clinical, biomarker, and safety data to inform decision-making
Contribute to regulatory documents (INDs, IBs, briefing packages) and regulatory interactions
Support investigator meetings, advisory boards, and external scientific communications
Ensure consistency of scientific messaging across internal and external stakeholders
Mentor and guide junior clinical scientists as the organization grows
Leverage AI-enabled tools to enhance clinical insights, literature analysis, data interpretation, and operational efficiency
Qualification
Required
PhD, PharmD, or equivalent advanced degree in life sciences, medicine, or a related field
10+ years of experience in clinical development or clinical sciences within biotech or pharmaceutical settings
Direct experience supporting or leading clinical trials (Phase 1–3 preferred)
Proven track record of contributing to successful clinical programs and regulatory milestones
Deep understanding of clinical trial design, endpoints, and regulatory requirements
Experience working with clinical data systems, trial databases, and scientific literature platforms
Familiarity with biomarker and translational data integration
Strong scientific writing and data presentation skills
Experience in rare disease, oncology, immunology, or other complex therapeutic areas (as applicable to Parabilis' pipeline)
Prior leadership or matrix-management experience
Experience interacting with regulatory agencies and external experts
Strong strategic thinking combined with hands-on execution
Comfort operating in a fast-paced, evolving biotech environment
Demonstrated use of AI tools in your current role and responsibilities is required
Preferred
Advanced or innovated use of AI is a strong plus
Benefits
Annual target bonus
Equity
Comprehensive suite of competitive benefits designed to support our employees’ overall well-being
Company
Parabilis Medicines
Parabilis Medicines™ is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for people living with cancer.
51-200 employees
H1B Sponsorship
Parabilis Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (4)
2023 (1)
2022 (2)
2020 (2)
Funding
Current Stage
Growth StageLeadership Team
Mathai Mammen, M.D., Ph.D.
Chairman, CEO and President
Weiqing Zhou
Co-founder & COO
Recent News
Google Patent
2025-05-04
Google Patent
2025-05-04
Company data provided by crunchbase