Tectonic Therapeutic, Inc. · 5 hours ago
Senior Information Technology Manager
Watertown, MA
Full-time
Hybrid
Senior Level
5+ years expTectonic Therapeutic, Inc. is a fast-growing biotech organization seeking a Senior Manager for IT Support. This role is responsible for leading and scaling the end-user technology environment, overseeing global service desk operations, and ensuring a secure and compliant IT environment across all labs and offices.
Biotechnology
Hiring Manager
Anthony Castiglia
Responsibilities
Lead, mentor, and develop the IT Support and Service Desk teams, ensuring a high-performance culture rooted in ownership, responsiveness, and exceptional customer service
Oversee day-to-day IT operations across offices and laboratories, ensuring business continuity and rapid issue resolution for scientific and clinical users
Manage and enforce ITIL-aligned processes including Incident, Request, Problem, Knowledge, and Change Management
Partner with Information Security to ensure endpoint controls, identity governance, patch compliance, and threat protection meet biotech-specific security requirements
Assist in the support of laboratory operations, scientific computing environments, and instrument-connected workstations in collaboration with Lab Operations and R&D teams
Ensure IT support processes align with GxP, 21 CFR Part 11, SOX, and data integrity requirements where applicable
Work with Quality Assurance on periodic reviews, CAPAs, audits, and validation documentation related to end-user systems and IT support processes
Support system readiness for regulatory inspections and internal/external audits
Lead the strategy and execution of enterprise endpoint management using modern management platforms (Intune, JAMF, UEM/MDM)
Own lifecycle management for all user devices including procurement, imaging/provisioning, configuration, maintenance, and secure disposal
Maintain secure standard operating environments (SOEs), OS hardening, automated software distribution, and global patching standards
Implement and maintain endpoint security technologies such as EDR, device encryption, vulnerability management tools, and compliance policies
Serve as an escalation point for complex Tier 3 technical issues, working closely with engineering and infrastructure teams
Lead the development and maintenance of knowledge base articles, SOPs, WI, user training programs, and self-service resources
Optimize onboarding and offboarding workflows, ensuring efficient provisioning of accounts, identity access, and hardware
Ensure all conference rooms, meeting spaces, and collaboration technology are fully operational, regularly maintained, and equipped with reliable AV, video conferencing, and connectivity solutions
Drive improvements in digital employee experience, leveraging analytics to reduce ticket volume and increase productivity
Oversee outsourced IT support providers, ensuring clear SLA governance, operational transparency, and continuous improvement
Manage hardware suppliers, lifecycle vendors, and professional services partners to sustain reliable end-user environments
Evaluate new technologies and services that improve support scalability, reliability, and cost-efficiency
Establish and maintain KPI reporting for service performance, SLA trends, endpoint compliance, asset lifecycle, and user satisfaction
Align support operations with corporate compliance, cybersecurity frameworks (NIST, CIS), and data privacy requirements
Identify areas for automation and process improvement, leading initiatives to streamline device provisioning, patching, and service workflows
Contribute to IT strategic planning, budgeting, and roadmap initiatives with a focus on scaling the organization
Qualification
Required
5+ years leading IT Support/Service Desk operations, with at least 3+ years in a management role
Exposure to supporting lab environments, scientific instruments, and hybrid GxP/non-GxP systems
Basic understanding of compliance frameworks (GxP, Part 11, SOX), change control, validation, and audit readiness
Proven expertise with Microsoft 365, Azure AD/Entra ID, and modern endpoint management platforms (Intune, JAMF, UEM)
Demonstrated success managing MSPs and external vendors
Strong cybersecurity awareness, including EDR, MFA, Zero Trust principles, and vulnerability management
Exceptional communication and interpersonal skills with an ability to support users ranging from lab scientists to executive leadership
Robust analytical and problem-solving abilities with experience developing KPI dashboards and service reports
Bachelor's degree in Information Technology, Computer Science, or related field, or equivalent hands-on experience
Ability to work onsite regularly to support labs and corporate operations (hybrid model)
Experience managing multiple concurrent initiatives, prioritizing efficiently, and communicating clearly across departments
Strong documentation habits, including SOPs, training materials, and operational reports
Ability to navigate and succeed in a dynamic, fast-paced biotech environment with evolving requirements
Preferred
biotech or life sciences experience strongly preferred
Company
Tectonic Therapeutic, Inc.
Tectonic is focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-Protein Coupled Receptors.
11-50 employees
H1B Sponsorship
Tectonic Therapeutic, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2023 (1)
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$395.7MKey Investors
Polaris Partners,Timothy A. Springer,Vida Ventures
2025-02-03Post Ipo Equity· $185M
2024-06-21IPO
2024-01-30Post Ipo Equity· $130.7M
Leadership Team
Daniel Lochner
Chief Financial Officer
Marcella (Marcie) Ruddy
Chief Medical Officer
Recent News
Tectonic Therapeutic
2025-11-07
Longevity.Technology - Latest News, Opinions, Analysis and Research
2025-11-04
Longevity.Technology - Latest News, Opinions, Analysis and Research
2025-11-04
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