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Pyramid Consulting, Inc · 1 day ago

MES ARCHITECT

United States

Contract

Remote

Senior Level

$65/hr - $70/hr

5+ years exp

Pyramid Consulting, Inc. is a leading IT Industry, and they are seeking a talented MES Architect for a contract opportunity with long-term potential. The role involves designing and delivering MES architectures, leading integration strategies, and ensuring compliance with industry standards while mentoring cross-functional teams.

ConsultingLegalSoftwareHuman ResourcesInformation TechnologyProfessional ServicesStaffing Agency

Growth Opportunities

H1B Sponsor Likely

Responsibilities

Must have skills: MES (Manufacturing Execution System), CSV, PA-X, SQL

Experience with Azure cloud providers, containerization, CI/CD for MES deployments, and infrastructure-as-code practices

Prior role as PAS X solution architect on full lifecycle implementations across multiple sites

Certifications in PAS X and formal training in GMP/CSV

Strong background in data migration strategies, analytics/OT data modeling, and MES operational reporting

Senior-level experience designing and delivering Werum PAS X MES architectures for pharmaceutical/biotech manufacturing, including multi-site and global deployments

Deep knowledge of MES concepts and standards (ISA 88, ISA 95) and how they translate into PAS X solution patterns, data models, and production templates

Responsibility for end-to-end solution architecture: logical & physical design, scalability, high availability, disaster recovery, capacity planning, and performance tuning

Lead integration strategy and design for peripheral systems (SAP, LIMS, ERP, PLC/SCADA, historians) using appropriate interface patterns (IDoc/XML/REST/OPC/web services) and middleware

Define validation approach and ensure architecture supports GMP, CSV, electronic signatures, audit trails, and 21 CFR Part 11 / Annex 11 compliance requirements

Strong expertise with infrastructure platforms (on prem and cloud), network/security considerations, Windows/SQL Server stacks, and deployment automation options

Establish governance, standards, and reusable reference architectures for PAS X configuration, release management, environment promotion, and configuration drift control

Create and review technical design documents, integration specifications, security designs, and validation deliverables; provide technical leadership in design reviews

Mentor and coordinate cross-functional teams (configuration engineers, QA, IT, automation engineers) and act as technical liaison with vendor(s) and stakeholders

Lead risk assessments, non functional requirements definition, cutover/rollout planning, and provide post go live architecture support and optimization

Proficiency with relational databases (Microsoft SQL Server), writing and debugging SQL queries, and supporting application-level data flows

Scripting or development skills for configuration tasks and automation (e.g., C#, .NET, JavaScript, or Python) and familiarity with version control tools

Experience producing technical documentation: design specs, configuration guides, validation deliverables, SOPs, and change control records

Excellent communication skills, ability to work with cross-functional teams (TQ / EQ, Production, IT), and willingness to travel for commissioning/support as required

Qualification

MESSQLPAS XAzureCI/CDGMP/CSVData migrationInfrastructure-as-codeTechnical documentationScripting skillsCommunication skillsCross-functional teamwork

Required