UW School of Medicine and Public Health · 4 hours ago
Researcher I or II
The UW School of Medicine and Public Health is seeking a Researcher I or II to join an immunology research team focused on investigating invariant natural killer T (iNKT) cells and developing novel immunotherapies. The successful candidate will conduct laboratory experiments, contribute to data analysis, and mentor undergraduate trainees in a collaborative environment.
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Responsibilities
Isolate and culture primary mammalian cells, and other cell lines to support laboratory experiments and collaborative efforts; generate preparations of antigens; generate stocks of purified and/or labeled monoclonal antibodies, recombinant fusion proteins, and other 'in-house' laboratory reagents
Troubleshoot and solve problems related to research techniques and protocols used in the lab
Carry out duties related to maintenance of mice for experimental use, including management/oversight of ordering, breeding, and experimental colonies
Supervise undergraduate student hourly workers and mentor undergraduates performing independent research projects in the lab
Conduct independent laboratory research under the guidance of the PI
Carry out duties related to laboratory management (e.g. oversight and ordering of supplies, maintenance of equipment and laboratory stocks, coordination of scheduling related to use of equipment and lab space, training others on use of equipment as needed)
Assist in developing grant applications and proposals to secure research funding
Qualification
Required
At least 6 years hands-on laboratory research experience in immunology or a related biological science discipline
Experience isolating, culturing, and analyzing primary human immune cells (T cells and/or NK cells required; experience with monocytes, macrophages, or dendritic cells a plus)
Proficiency performing common immunoassays (e.g., ELISA, ELISpot, cytotoxicity, lymphocyte proliferation)
Experience working with murine models, including basic in vivo procedures and support of mouse colony maintenance (breeding, genotyping, husbandry)
Experience analyzing flow cytometry data using FlowJo or similar software
At least 6 years hands‑on laboratory research experience in immunology or a related biological science, with the ability to independently execute experimental workflows
Experience isolating, culturing, and analyzing primary human immune cells, including T cells and/or NK cells (experience with monocytes, macrophages, or dendritic cells beneficial)
Proficiency in performing a range of immunoassays, such as ELISA, ELISpot, cytotoxicity assays, and lymphocyte proliferation assays, with the ability to troubleshoot and optimize assays as needed
Experience working with murine models, including performing routine in vivo procedures and independently supporting mouse colony management (breeding, genotyping, and husbandry)
Experience conducting and interpreting flow cytometry experiments, including data analysis using FlowJo or similar software
MS required, majoring in Biological Sciences or equivalent
Preferred
Experience isolating and culturing primary human tumor cells or tumor‑infiltrating lymphocytes (TILs), including work with tumor spheroid/organoid cultures
Experience supporting in vitro assays to evaluate anti‑tumor immune responses and familiarity with xenograft mouse models involving human tumor or immune cells
Experience with histology, fluorescence microscopy, and/or live‑cell imaging systems (e.g., IncuCyte)
Experience performing molecular biology techniques such as real‑time PCR (qPCR) and transcriptomic/genomic analyses (e.g., RNA‑seq, ATAC‑seq, ChIP‑seq)
Experience with protein analysis techniques, including immunoprecipitation and Western blotting
Experience designing, optimizing, or troubleshooting assays involving primary human immune cells or related cellular models
Demonstrated ability to independently analyze data, troubleshoot technical issues, and contribute to experimental planning
Strong organizational skills and experience coordinating research activities within a team environment
Benefits
Generous vacation
Holidays
Sick leave
Competitive insurances and savings accounts
Retirement benefits
Company
UW School of Medicine and Public Health
UW School of Medicine and Public Health offers graduate programs, health professions programs, and innovative research. It is a sub-organization of University of Wisconsin-Madison.
Funding
Current Stage
Late StageTotal Funding
$1.1MKey Investors
American Medical Association
2026-01-13Grant· $1.1M
Recent News
2025-11-03
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