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Software Engineer - .NET Full Stack Developer jobs in United States
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Mayo Clinic · 1 week ago

Software Engineer - .NET Full Stack Developer

Mayo Clinic is a top-ranked healthcare provider dedicated to patient care and employee support. They are seeking a Software Engineer to design, develop, and maintain .NET-based back-end services for genomics and clinical applications, ensuring performance and reliability while collaborating with cross-functional teams.
BiotechnologyHealthcareHospitalWellnessHealth CareMedical
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Responsibilities

Design, develop, and maintain robust .NET-based back-end services supporting a broad portfolio of genomics and clinical applications
Build and optimize services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing
Ensure that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems
Collaborate closely with Product Owners, Product Managers, Architects, and cross-functional engineering partners to translate requirements into well-architected, maintainable code
Design and implement services aligned to enterprise architecture, including cloud-ready APIs, data integration pipelines, and secure interoperability layers for genomic systems
Participate in Agile and DevOps practices using GitHub, Azure DevOps (ADO), Azure Pipelines, and CI/CD frameworks
Work may include deployment automation and configuration management using tools such as ARM/Bicep, Terraform, Cloud Build, or Azure Pipelines, supporting both on-prem and cloud-hosted applications
Maintain comprehensive technical documentation, contribute to code reviews, and participate in expert-level troubleshooting through log analysis, root cause evaluation, and data/system investigation
Communicate effectively with peers, leaders, and clinical partners across the organization
Build knowledge of genomics workflows, organizational processes, and customer needs while performing a range of technical assignments with moderate guidance and increasing autonomy

Qualification

Software EngineeringC#CC++GolangJavaModern application development frameworks.NET technologiesRESTful APIsMicroservicesWeb servicesDevOps pipelinesCI/CDAzure DevOpsGitHub ActionsAzure PipelinesRelational databasesNoSQL databasesAnalytics platformsBig data processingEnterprise data pipelinesDistributed systemsHybrid cloud environmentsAzureGoogle Cloud Platform (GCP)Healthcare software developmentBioinformaticsGenomics applicationsSecure coding practicesAgile software development

Required

Bachelor's degree in computer science/engineering or related field; Or an associate's degree in computer science/engineering or related field with an additional 2 years of experience as described below
Have working knowledge and experience of Software Engineering with a minimum of internships and a minimum of 1 year of experience, or 2 years of experience coding applications or services in a high-level language (C, C++, Golang, Java, C# etc.)
Demonstrated problem solving and time management skills
Possesses strong technical aptitude for designing and implementing software solutions
Experience with modern application development frameworks
Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations
Deep hands-on technical expertise, excellent verbal and written communication skills
Experience with Agile software development techniques

Preferred

Experience developing applications in hybrid environments, including on-premises systems, Azure, and Google Cloud Platform (GCP)
Familiarity with building and integrating RESTful APIs, microservices, and web services using .NET technologies
Knowledge of DevOps pipelines and CI/CD using Azure DevOps, GitHub Actions, or Azure Pipelines
Utilization of AI coding tool such as GitHub CoPilot, Gemini, Claude
Experience with relational and NoSQL databases, analytics platforms, big-data processing, or enterprise data pipelines
Background in developing high-performance, scalable, and highly available distributed systems
Experience supporting or developing solutions in healthcare, clinical, Bioinformatics or genomics-focused applications is highly desirable
Ability to use a wide variety of open-source technologies and cloud-based services
Experience with Google and Azure cloud environments
Experience in databases, analytics, big data systems or business intelligence products
Experience with building high-performance, highly available and scalable distributed systems
Experience developing software for healthcare related industries

Benefits

Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.

Company

Mayo Clinic

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MayoClinic is a nonprofit medical practice and medical research group focused on integrated health care, education, and research.

Funding

Current Stage
Late Stage
Total Funding
$399.05M
Key Investors
The ALS AssociationNational Institute of Neurological Disorders and StrokeAmerican Heart Association
2025-12-04Grant· $0.95M
2024-09-24Grant· $12M
2023-07-26Grant

Leadership Team

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Gianrico Farrugia
President and CEO
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Richard Gray
Chief Executive Officer
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Company data provided by crunchbase