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PK/PD Principal Scientist jobs in United States
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Zoetis · 23 hours ago

PK/PD Principal Scientist

Zoetis, a global leader in animal health, seeks an enthusiastic colleague to join our Veterinary Medicine Research and Development (VMRD) PK/PD Scientist Team to discover and develop novel therapeutics for veterinary medicine. The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK/PD studies in multiple species in support of projects from early research through late-stage development.
AgricultureBiotechnologyHealthcarePetPharmaceuticalHealth CareMedicalVeterinary
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Independently design and analyze *in vivo* PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports
Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens
Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects
Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions
Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project
Present research results to scientific teams, management, and regulatory agencies
Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents

Qualification

PharmacologyBiochemistryVivo PK studiesVivo PK/PD studiesBiotherapeuticsPKPK/PD analysis softwareWinNonlinMonolixWatsonBioanalytical methodologyADA assaysImmunogenicity assessmentPK/PD modelingSimulationPBPK modelingQSP modelingPopulation PK modelingNONMEMR softwareRegulatory submissionsGLP studies

Required

Ph.D in pharmacology, biochemistry, or related field with 4 or more years of relevant pharmaceutical development experience
Proven ability to design, analyze and interpret in vivo PK and PK/PD studies
Skilled in the use of PK and PK/PD analysis software such as WinNonlin, Monolix or Watson
Must have excellent verbal & written communication skills
Self-starter, able to prioritize work and work efficiently with minimal supervision
Working knowledge of bioanalytical methodology

Preferred

DVM DACVCP or DVM Dipl. ECVPT is highly desirable
Experience with biotherapeutics (protein therapeutics) is highly desirable
Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics is highly desirable
Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable
Experience interacting with regulatory agencies is highly desirable
Experience conducting GLP studies is desirable

Benefits

Healthcare and insurance benefits beginning on day one
A 401K plan with a match and profit-sharing contribution from Zoetis
4 weeks of vacation

Company

Zoetis is an animal health company that advances care for animals and supports their health and wellbeing.

H1B Sponsorship

Zoetis has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
67%
Represents job field similar to this job
Engineering and Development
Management and Executive
Product Management
Accounting and Finance
Customer Service and Support
Marketing
Sales
Legal and Compliance
Education and Training
Human Resources
Trends of Total Sponsorships
*2026 (15)
2025 (136)
2024 (80)
2023 (89)
2022 (126)
2021 (47)
2020 (63)

Funding

Current Stage
Public Company
Total Funding
$3.62B
Key Investors
Bill & Melinda Gates Foundation
2025-12-16Post Ipo Debt· $1.75B
2025-08-11Post Ipo Debt· $1.85B
2023-03-01Grant· $15.3M

Leadership Team

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Kristin Peck
Chief Executive Officer
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Oliver Boucher
Vice President
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Company data provided by crunchbase