Alnylam Pharmaceuticals · 1 day ago
Scientist, CNS Biology Research
United States
Full-time
Remote
Entry, Mid Level
$110K/yr - $166K/yr
1+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, seeking a motivated Scientist to join their CNS Biology Research team. The role involves identifying and validating novel drug targets for neurodegenerative diseases while collaborating with multidisciplinary teams to advance programs through clinical stages.
BiotechnologyHealthcarePharmaceuticalHealth CareMedicalTherapeutics
Responsibilities
Contribute to Alnylam’s growing pipeline by identifying new siRNA drug-targets that are based on human genetics, literature, academic collaborations, genomic approaches, etc. across the neurodegenerative space
Design and execute proof of concept experiments in animal and in vitro iPSC disease models
Design studies, coordinate activities, and lead from the bench
Serve as Biology Lead on select neurodegenerative/neuromuscular programs, overseeing lead discovery activities for the selection of drug candidates for further development
Work with multifunctional teams to shepherd a drug candidate through the lead selection and development process to the clinic
Support programs through CTA/IND filing processes
Manage relationships with contract research organizations (CROs) and/or academic collaborators, including development of research plans and data analysis
Mentor junior scientists
Collaborate and communicate results with key stakeholders throughout organization and external partners
Qualification
Required
PhD in biology or biomedical sciences-related field
Strong publication record
In vitro technical skills including RNA and protein quantification, high-content image-based and functional assays related to disease biology, and single-cell RNA sequencing
Strong organizational skills with the ability to proactively multitask are a must
Excellent interpersonal and communication skills with proven ability to work collaboratively in a fast-paced team environment
Genuine curiosity for learning new biology and a passion for hands-on laboratory work
Preferred
Post doc in academia or industry or 1-2 years of experience preferred
Individuals with expertise in Amyotrophic Lateral Sclerosis (ALS) are strongly encouraged to apply
Thorough understanding of relevant in vivo mammalian disease models strongly preferred, with experience in intracerebroventricular (ICV) injections, necropsy, behavioral analysis, ex vivo tissue processing, and downstream analysis including molecular and histological assessments
Benefits
Annual short-term incentive award (e.g., bonus or sales incentive)
Annual long-term incentive award (e.g., equity)
Medical, dental, and vision coverage
Life and disability insurance
Lifestyle reimbursement program
Flexible spending and health savings accounts
401(k)with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
75%
Represents job field similar to this job
Engineering and Development
Management and Executive
Legal and Compliance
Customer Service and Support
Trends of Total Sponsorships
*2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
2026-07-10
Investor's Business Daily
2026-07-10
2026-07-10
Company data provided by crunchbase