Alnylam Pharmaceuticals · 2 weeks ago
Scientist, Target Discovery & Validation
United States
Full-time
Remote
Mid Level
$110K/yr - $166K/yr
1+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, and they are seeking a motivated Scientist in the Target Discovery and Validation group. The role involves identifying novel drug targets and leading preclinical studies to validate these targets.
BiotechnologyHealthcarePharmaceuticalHealth CareMedicalTherapeutics
Responsibilities
Work closely with Alnylam’s human genetics, multi-omics, platform and clinical teams to identify promising novel targets
Contribute to Alnylam’s target identification efforts that are based on human genetics, literature, academic collaborations, genomic approaches, etc
Design and execute proof of concept experiments in animal and in vitro disease models
Design studies, coordinate activities, and lead from the bench
Oversee lead discovery activities for the selection of drug candidates for further development
Develop assays to monitor target engagement/pharmacodynamic responses
Manage relationships with contract research organizations (CROs) and/or academic collaborators, including development of research plans and data analysis
Mentor junior scientists
Collaborate and communicate results with key stakeholders throughout organization
Qualification
Required
PhD in biology or biomedical sciences-related field
Strong publication record
Solid organizational skills and ability to multitask are a must
The successful candidate will have strong interpersonal and communication skills, track record of working on teams, interest in learning new biology and passion for lab work
Preferred
Post doc or 1-2 years of experience strongly preferred
Existing focus on disease biology and prior experience with mammalian disease models is also preferred
Experience in using human genetics to support biological mechanisms is a plus
Benefits
Annual short-term incentive award (e.g., bonus or sales incentive)
Annual long-term incentive award (e.g., equity)
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
401(k)with a generous company match
Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
75%
Represents job field similar to this job
Engineering and Development
Management and Executive
Legal and Compliance
Customer Service and Support
Trends of Total Sponsorships
*2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
BioWorld Financial Watch
2026-07-18
2026-07-10
Company data provided by crunchbase