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Senior Scientist, Cell Biology jobs in United States
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Alnylam Pharmaceuticals · 1 day ago

Senior Scientist, Cell Biology

Alnylam Pharmaceuticals is a leader in RNAi therapeutics, and they are seeking a highly motivated Senior Scientist in Delivery Biology to support targeted delivery strategies for siRNA-based therapeutics. The role focuses on mechanistic cell biology to improve delivery across tissues and cell types, requiring excellent collaboration and communication skills.
BiotechnologyHealthcarePharmaceuticalHealth CareMedicalTherapeutics
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Comp. & Benefits
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Responsibilities

Develop and apply assays and experimental strategies to interrogate trafficking biology
Design, execute, and interpret cell‑based assays to evaluate delivery efficiency and biological outcomes
Identify cell types or tissues that require novel or optimized delivery approaches
Collaborate extensively with cross‑functional partners focused on expanding targeted delivery into new cell types and tissues
Transparently communicate data, conclusions, and experimental rationale to team members and leadership
Mentor and support the scientific development of junior scientists or research associates

Qualification

Cell BiologyIntracellular TraffickingReceptor BiologyMicroscopyBiochemical TechniquesVitro ExperimentationVivo ExperimentationLigand-based DeliveryOligonucleotide Conjugates

Required

PhD in Cell Biology, Molecular Biology, Immunology, Biochemistry or related field
2-3 years of experience in biopharma setting
Strong expertise in cell biology, particularly intracellular trafficking, receptor biology, or related mechanisms
Experience in microscopy and biochemical techniques related to cell-based studies
Experience designing and interpreting both in vitro and in vivo experiments
Demonstrated scientific rigor, attention to detail and data reproducibility
Excellent communication and interpersonal skills, with the ability to effectively collaborate across multidisciplinary teams

Preferred

Experience with ligand-based delivery, conjugates or receptor biology preferred

Benefits

Annual short-term incentive award (e.g., bonus or sales incentive)
Annual long-term incentive award (e.g., equity)
Medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
401(k)with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave

Company

Alnylam Pharmaceuticals

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Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.

Funding

Current Stage
Public Company
Total Funding
$4.55B
Key Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO

Leadership Team

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Yvonne Greenstreet
Chief Executive Officer
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Jeff Poulton
Chief Financial Officer
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Company data provided by crunchbase