Amgen · 1 month ago
Senior Machine Learning Engineer
United States
Full-time
Remote
Senior Level
$156K/yr - $211K/yr
2+ years expAmgen is a leading biotechnology company focused on serving patients living with serious illnesses. They are seeking a Senior Machine Learning Engineer to build scalable AI proofs-of-concept and collaborate with product managers and business stakeholders to translate business needs into practical AI solutions.
BiotechnologyHealthcareManufacturingPharmaceuticalHealth Care
Responsibilities
Build scalable AI proof-of-concepts that are designed to demonstrate a clear path from prototype to enterprise-scale solution
Partner with product managers, business stakeholders, platform teams, and AI & software engineers to translate ambiguous business needs into practical AI solutions with measurable value
Design and implement modern AI systems using LLMs, agentic workflows, retrieval-augmented generation, data pipelines, APIs, cloud-native services, and enterprise platforms
Rapidly validate feasibility and value by assessing technical risk, data readiness, integration complexity, user experience, security considerations, performance, cost, and business impact
Create reusable technical assets such as reference architectures, reusable components, documentation, decision records, and handoff materials that enable product, platform, or delivery teams to scale successful POCs
Raise the technical bar for the team by modeling strong engineering practices, mentoring others, improving delivery patterns, and bringing clear ownership and accountability to uncertain, fast-moving work
Qualification
Required
Doctorate degree
Master's degree and 2 years of relevant experience
Bachelor's degree and 4 years of relevant experience
Associate's degree and 8 years of relevant experience
High school diploma / GED and 10 years of relevant experience
Preferred
4-6 years of relevant experience in AI engineering, machine learning engineering, software engineering, data engineering, cloud engineering, or related technical roles
Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind
Strong understanding of modern AI application architecture, including LLMs, retrieval-augmented generation, embeddings, vector databases, agentic workflows, tool use, orchestration frameworks, and AI evaluation methods
Experience defining and applying evaluation methods for AI solutions, including accuracy, reliability, hallucination risk, latency, usability, safety, cost, and fitness for intended use
Ability to translate ambiguous business problems into practical technical approaches, make sound tradeoffs, and rapidly validate feasibility, value, risks, and path to scale
Experience with AWS Cloud, data pipelines, integration architecture, containers, CI/CD, observability, and secure development practices
Strong software engineering foundation, preferably with Python and modern development practices, including testing, version control, modular design, documentation, and maintainable code
Demonstrated ability to responsibly use AI tools to improve engineering productivity, explore technical solutions, automate repetitive tasks, and enhance the delivery of machine learning or software products
Excellent communication, ownership, and cross-functional leadership skills, with the ability to partner effectively with product managers, business stakeholders, platform teams, and AI and software engineers
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
72%
Represents job field similar to this job
Engineering and Development
Management and Executive
Accounting and Finance
Marketing
Legal and Compliance
Customer Service and Support
Sales
Product Management
Education and Training
Human Resources
Public Sector and Government
Trends of Total Sponsorships
*2026 (130)
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chief Executive Officer
Gilles Marrache
Senior Vice President General Manager Europe, Latin-America, Middle-East Africa, Canada
Recent News
2026-07-12
Company data provided by crunchbase