Veracyte, Inc. · 2 weeks ago
Senior Bioinformatics Scientist
United States
Full-time
Remote
Senior Level
$170K/yr - $187K/yr
6+ years expVeracyte, Inc. is a global diagnostics company committed to transforming cancer care for patients. They are seeking a highly experienced Senior Bioinformatics Scientist to drive the design and development of next-generation minimal residual disease laboratory-developed tests, contributing to assay concepts and collaborating with cross-functional teams to deliver clinically actionable diagnostics.
BiotechnologyHealthcareMedical DeviceHealth CareHealth Diagnostics
No H1B
Responsibilities
Contribute to bioinformatics strategy for MRD assay design, development, optimization, and lifecycle management for LDTs developed under CAP/CLIA quality systems
Lead and contribute to study design, data analysis, performance characterization, and decision‑making throughout development
Apply deep domain knowledge in cancer genomics, ctDNA biology, and NGS technologies to inform assay architecture, variant detection strategies, and error suppression approaches in collaboration with our data science and modeling teams
Design and execute analytical studies to evaluate assay performance, including accuracy, limit of detection, and reproducibility, in collaboration with wet‑lab and biostatistics partners
Develop, validate, and maintain scalable, production‑ready bioinformatics pipelines for MRD analysis, including QC, variant calling, MRD calling logic, and reporting
Lead benchmarking and optimization of computational methods, including background error modeling, and longitudinal MRD tracking
Ensure compliance with standards (CAP/CLIA, FDA, IVDR) throughout the bioinformatics development lifecycle, including rigorous testing and documentation
Partner closely with molecular biology, assay development, QA/RA, clinical, and software engineering teams to ensure bioinformatics solutions are aligned with assay design, regulatory expectations, and operational constraints
Contribute to regulatory submissions and audits by providing technical documentation and validation report, and responses to audits or regulatory inquiries
Provide technical mentorship and scientific guidance to junior scientists, helping raise the overall bar of assay development rigor and execution
Communicate complex analytical concepts and results clearly to both computational and non‑computational stakeholders, including senior leadership
Qualification
Required
Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field. (or M.Sc. plus 3 additional years industry experience)
Minimum 6 years of total relevant experience in biotech, diagnostics, or regulated healthcare environments
Demonstrated experience in NGS‑based assay development for clinical diagnostics. Hands‑on experience with ctDNA‑based MRD assays, including personalized or tumor‑informed approaches
Strong programming skills in Python, with experience developing reproducible, production‑grade analysis pipelines, including experience with SDLC best practices
Proven experience working in design‑controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent)
Proficiency in development of novel bioinformatics methodologies, and algorithms development, including benchmarking of computational methods
Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team
Demonstrated record of technical and scientific ownership, and independent work
Preferred
Experience developing and deploying bioinformatics workflows in AWS (e.g., EC2, S3, Step Functions, Batch, Lambda, etc.)
Strong understanding of germline and somatic mutation processes leading to complex variation and genome-wide biomarkers with potential clinical utility
Working knowledge of R
Experience with relational and non-relational database technologies is a plus
Benefits
May be eligible for additional discretionary bonuses/incentives
Restricted stock units
Competitive compensation and benefits
Committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions
Recognized as a 2024 Certified™ Great Place to Work® in both the US and Israel
Company
Veracyte, Inc.
Veracyte is a global diagnostics company that empowers clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer.
501-1000 employees
Funding
Current Stage
Public CompanyTotal Funding
$1.1BKey Investors
Visium Healthcare PartnersGE VenturesDomain Associates
2021-02-05Post Ipo Equity· $550M
2020-08-05Post Ipo Equity· $194M
2019-05-01Post Ipo Equity· $137.8M
Leadership Team
Marc Stapley
Chief Executive Officer
John Leite
Chief Commercial Officer (CCO)
Recent News
2026-08-02
2026-07-30
Company data provided by crunchbase