Penn State University · 1 month ago
Research Technologist – iPSC Cell Culture and Genome Engineering
Penn State University is seeking a Research Technologist to join a cardiovascular research laboratory studying inherited cardiac diseases using human induced pluripotent stem cell models. The role focuses on maintaining and differentiating iPSC cultures, conducting genome engineering and molecular assays, documenting experiments, analyzing data, and supporting collaborative translational research.
EducationHigher EducationTrainingUniversities
No H1B
Responsibilities
Perform routine maintenance, expansion, cryopreservation, and quality control of human iPSC lines
Differentiate iPSCs into cardiomyocytes and other relevant cell types following established protocols
Isolate and expand single-cell clones and perform molecular validation using PCR, Sanger sequencing, and related techniques
Conduct molecular and cellular assays including DNA/RNA extraction, qPCR, Western blotting, immunofluorescence staining, and flow cytometry as needed
Maintain accurate laboratory records, experimental documentation, and electronic databases
Prepare reagents, maintain cell culture supplies, and ensure compliance with laboratory safety procedures
Assist in data analysis, figure preparation, and presentation of research findings
Participate in laboratory meetings and contribute to collaborative research projects
Qualification
Required
Experience with mammalian cell culture
Strong organizational skills and attention to detail
Excellent written and verbal communication skills
Ability to work independently while contributing effectively within a collaborative research team
Bachelor's Degree
1+ years of relevant experience; or an equivalent combination of education and experience accepted
Applicants must be authorized to work in the U.S
Preferred
Bachelor's or master's degree in Cell Biology, Molecular Biology, Genetics, Biomedical Sciences, Biotechnology, or a related field
Experience culturing human iPSCs or embryonic stem cells
Experience with stem cell differentiation, particularly cardiac differentiation
Familiarity with PCR, cloning, DNA sequencing, and molecular biology techniques
Experience with fluorescence microscopy, flow cytometry, or next-generation sequencing is desirable
Prior experience in cardiovascular, stem cell, or genetic disease research
Strong motivation to learn new techniques
Excellent problem-solving and troubleshooting skills
Ability to manage multiple projects simultaneously
Commitment to maintaining rigorous scientific standards and reproducible research
Interest in translational medicine and cardiovascular genetics
Benefits
Comprehensive medical, dental, and vision coverage
Robust retirement plans
Substantial paid time off which includes holidays, vacation and sick time
Generous 75% tuition discount, available to employees as well as eligible spouses and children
Company
Penn State University
Public university educating students worldwide.
Funding
Current Stage
Late StageTotal Funding
$15.41MKey Investors
US Department of EnergyAlfred P. Sloan FoundationNational Institutes of Health
2024-04-11Grant· $0.82M
2022-01-01Grant· $1.19M
2018-11-13Grant· $13.4M
Leadership Team
Jay Davenport
Vice President for Development and Alumni Relations
Broach James
Distinguished Professor and Chair, Biochemistry and Molecular Biology
Recent News
LinkedIn
2026-09-02
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