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Flagship Pioneering ยท 2 days ago
Associate Director, Tissue Culture and Cell Engineering
Cambridge, MA
Full-time
Onsite
Director
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Responsibilities
Serve as inaugural member of the tissue, leading establishment of lab processes and workflows, and growth of the tissue
Drive team excellence by recruiting, training, and mentoring a high-performance tissue culture and cell engineering group.
Lead and implement development of cell culture best practices, owning cell line onboarding, maintenance, expansion, cryopreservation, cataloging, and QC of new cell lines across the organization.
Work closely with cross-functional teams (e.g., Protein Sciences, Translational, Automation) to establish optimal assay protocols, conditions, and SOPs for key workflows across protein sciences and assay development.
Assess integration of new tissue culture approaches into core workflows, including primary tissues and organoids.
Develop and implement process improvements and technological advancements to enhance yield, scale, quality, purity and other key outputs.
Manage budgets, timelines, request queue, and resources to meet organizational and project-specific goals.
Implement inventory tracking, cell banking, and rigorous metadata capture/annotation via ELN and other LIMS systems.
Establish and manage tissue culture facility operations, adhering to latest industry standards.
Qualification
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Required
BS/BA, MS of relevant industry experience. Industry experience required.
Strong expertise in mammalian cell culture (adherent & suspension cultures, stable cell lines, inducible systems, etc.), and primary cells.
Proven experience with novel cell line generation and diverse methods for stable or transient protein expression, such as transfections, transductions, electroporation, etc.
Proven hands-on experience with cell-based and molecular biology assays such as: cell viability/cytotoxicity, flow cytometry, mRNA expression analysis (qPCR/ddPCR/RNA-seq), western blotting, ELISA among others.
Experienced managing various ELN and LIMS systems and ensuring team compliance.
Excellent communication skills and ability to work in a highly collaborative and cross-functional way.
A strong self-starter, resourceful, independent thinker, with excellent attention to details. Ability to work independently and make critical decisions.
Eager to work with highly skilled and dynamic teams in a fast-paced, entrepreneurial, and technical setting.
Experience managing multiple direct reports.
Preferred
Experience working with automation and automated high-throughput cell culture processes.
Queue management experience in a service-oriented manner; this position interfaces with all functional groups with continuous high demand.
Experience working collaboratively with computational biology and machine learning scientists for de novo protein design.
Company
Flagship Pioneering
Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.
Founded in 2000
201-500 employees
H1B Sponsorship
Flagship Pioneering has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Trends of Total Sponsorships
2023 (5)
2022 (5)
2021 (1)
Funding
Current Stage
Growth StageLeadership Team
Diego Miralles
CEO and Partner
John Lepore
CEO-Partner
Recent News
2024-04-24
Company data provided by crunchbase
