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Company

Original Job Post

Merck · 2 days ago

Director, Biologics Production and Engineering

Boston, MA

Full-time

Hybrid

Director

8+ years exp

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Comp. & Benefits

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Responsibilities

Lead a team of scientists in Boston Discovery Biologics to design, produce and characterize a wide variety of protein therapeutic molecules to identify strong candidates for development

Work across groups and departments to set and deliver on strategic goals in scientific excellence, talent development, and pipeline advancement

Lead and participate in cross-functional project teams to deliver impactful protein therapeutics from discovery to development

Ideate and initiate new program concepts leading to pipeline programs in partnership with therapeutic area scientists

Partner across multidisciplinary interfaces to achieve organizational objectives

Attract and develop talent, including leveraging diversity to strengthen the team

Foster a high-performance culture of collaboration, engagement, self-accountability, and inclusion

Manage priorities, resources, and investments aligned with the Discovery Biologics strategy

Stay abreast of external advancements in relevant scientific fields

Promote the external reputation of the company's Discovery Biologics

Qualification

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Biologics discoveryProtein therapeuticsScientific knowledgeInnovationsPeople managementPublication recordProtein engineeringExpressionPurificationCharacterizationPreclinical developmentExternal reputationLeadershipCommunicationCollaborationTalent developmentDiverseInclusive cultureComputational MethodsStructure-Based MethodsDevelopability AssessmentLab AutomationAutomated WorkflowsOutsourcingCollaboration ManagementDue DiligenceBusiness Development

Required

PhD in life sciences with 8+ years of substantial industry experience, MS with 10+ years of experience, or BS with 14+ years of experience. A mix of industrial and relevant academic experience can be considered.

Track record in leadership and managerial roles in biologics discovery

Experience in advancing protein therapeutics through discovery to development

Strong presentation and publication record

Excellent communication and collaboration abilities

Deep scientific knowledge of the workflows required for the discovery of protein therapeutics

Strong technical knowledge of multiple aspects of biologics production including protein engineering, expression, purification, and characterization.

Project leadership experience across Discovery stages, from tool-molecule generation through preclinical development of therapeutic candidates

Track record of driving scientific or platform innovations

Demonstrated passion for and a track record of talent development

Prior direct people management of 4-5+ FTEs

Established external reputation through high-impact publications, presentations, and/or scientific community engagement

Champion for diverse and inclusive culture

Preferred

Ideal candidate will have experience in protein therapeutics beyond traditional mAbs including alternative non-Ig scaffolds, bi- or multispecifics, fusion proteins, and ADCs.

Protein engineering through computational and structure-based methods.

Developability assessment of protein therapeutics

Experience in lab automation, including automated production workflows

Experience in outsourcing and managing external collaborations

Prior experience in due diligence and business development activities