Be an early applicantLess than 25 applicants

Company

Entrada Therapeutics · 19 hours ago

Principal Scientist, DMPK

Boston, MA

Full-time

Remote

Senior Level, Lead/Staff

12+ years exp

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BiotechnologyEmergency Medicine

H1B Sponsor Likely

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Responsibilities

Lead all PK- and ADME-related efforts for designated program(s).

Communicate and present relevant information across all areas of the organization, regardless of level.

Select and manage PK/TK, PK/PD, and ADME CROs.

Author and review PK/TK, PK/PD, and ADME reports.

Author and review relevant PK/TK, PK/PD, and ADME sections of regulatory submission documents (e.g. investigational new drug (IND), investigator brochure (IB), clinical trial application (CTA), etc)

Review associated reports, including clinical, toxicology, pharmacology, and bioanalysis.

Collaborate with clinical teams, including pharmacology, biomarkers, development, and operations.

Collaborate with non-clinical development teams, including toxicology and bioanalysis.

Collaborate with discovery teams to guide future programs and better understand mechanisms of action.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

PharmacologyDMPK experienceADME studiesVendor ManagementBioanalytical techniquesPK/PD modelingTranslational biologyOligonucleotide modalitiesAuthoring reportsCommunicatorCollaborative

Required

PhD in pharmacology or similar field with 8+ years of DMPK experience in an industry setting or a MS with 12+ years of relevant experience.

Expertise with ADME studies and assays, with a proven track record of strategizing and troubleshooting based upon raw data.

Vendor Management experience, specifically managing CROs.

Experience authoring and reviewing DMPK-related reports and regulatory documents for health authority submissions.

Ability to multi-task effectively and work within aggressive timelines.

Preferred

Additional experience with other aspects of ADME, bioanalytical techniques, PK/PD, toxicokinetics, pre-clinical PK/PD modeling, and translational biology.

Experience with oligonucleotide-based modalities.

Benefits

Competitive health, dental, and vision coverage

Life insurance

Short term and long-term disability insurance

Discretionary time off

Paternity leave

Excellent 401(k) package

Generous transportation stipend

Company

Entrada Therapeutics

Entrada Therapeutics is a developer of novel therapeutics intended to treat devastating diseases.

Founded in 2016

Boston, Massachusetts, USA

51-200 employees

https://www.entradatx.com

H1B Sponsorship

Entrada Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2023 (4)

2022 (6)

2021 (1)

2020 (1)