Principal Scientist - Neurodegeneration @ Novartis | Jobright.ai
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Principal Scientist - Neurodegeneration jobs in Cambridge, MAH1B Visa Sponsored Principal Scientist - Neurodegeneration jobs in Cambridge, MA
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Novartis · 2 days ago

Principal Scientist - Neurodegeneration

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Responsibilities

Contribute to creating and developing novel therapeutic strategies for Parkinson's disease, with an emphasis on mitochondrial/lysosomal function and dysfunction. Communicate project strategy, scientific vision, and data to key stakeholders.
Lead and/or engage in the design, execution, and analysis of experiments to deliver high quality data and enable project decisions. Deliver impact to projects by following both technical and conceptual trends in the neurodegeneration field.
Develop and integrate models of Parkinson's disease using both in vitro and in vivo systems in collaboration with multi-disciplinary teams in BR.
Collaborate with multidisciplinary teams, consisting of experts in molecular biology, drug discovery, and biochemistry. Expertly relay information to all levels of the organization, as well as with our external partners and collaborators.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

Parkinson's Disease PathophysiologyCell BiologyMitochondrial PathwaysLysosomal Pathways Vitro Models Vivo ModelsDisease ProgressionLaboratory MethodologiesNeuroscienceBiochemistryImagingMolecular ProfilingComplianceLaboratory SafetyAnimal WelfareRegulatory RequirementsProblem-SolvingAttention to DetailCreativityOrganizational SkillsInterpersonal SkillsCommunication SkillsLeadershipHuman iPS-derived neuronal modelsStereotaxic surgeries in rodents

Required

Master’s Degree in Neuroscience, Cell biology or a closely related field, and 6+ years of specific expertise on the molecular and cellular mechanisms of Parkinson's Disease.
A deep understanding of the pathophysiology of Parkinson’s disease and its interface with cell biological mechanisms, preferably related to mitochondrial and lysosomal pathways.
Demonstrated expertise in establishing both in vitro and in vivo models of Parkinson's disease to study disease progression and mechanisms.
Exceptional proficiency in various laboratory methodologies within neuroscience and neuronal cell biology including biochemistry, imaging and molecular profiling.
Excellent problem-solving skills, diligent attention to detail, and the ability to work both independently and as a member of a complex matrix teams. Thinking creatively to tackle scientific and operational challenges in a fast-paced drug discovery environment
Strong organizational, interpersonal, and communication skills. Proven track record in leading collaborative projects.
Strict adherence to compliance with institutional policies, laboratory safety and animal welfare guidelines, and regulatory requirements.

Preferred

PhD and related Post-Doc
Experience in human iPS-derived neuronal models.
Experience in stereotaxic surgeries in rodents.

Benefits

401(k) eligibility
Various paid time off benefits, such as vacation, sick time, and parental leave

Company

Novartis

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Novartis is a healthcare company that provides solutions to address the evolving needs of patients worldwide.

H1B Sponsorship

Novartis has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Trends of Total Sponsorships
2023 (17)
2022 (18)
2021 (42)
2020 (26)

Funding

Current Stage
Public Company
Total Funding
$6.5M
Key Investors
Bill & Melinda Gates Foundation
2018-02-14Grant· $6.5M
2000-05-19IPO· nyse:NVS

Leadership Team

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Bharti Rai
VP Commercial Operations/Effectiveness, Insights and Analytics, US Pharma Executive Committee Member
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Daniel Grant
Vice President & Global Program Head
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Company data provided by crunchbase
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