Boehringer Ingelheim · 2 days ago
Scientist III/IV, Biophysical Developability Assessments
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BiotechnologyHealth Care
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Responsibilities
Perform stage appropriate biophysical developability assessments, including biophysical screening of protein attributes on automated platforms, assessing solution behavior, stability, interpret and present findings to other Biotherapeutics Discovery colleagues.
Develop novel analytical methodologies and evaluate new technologies to improve the overall developability strategy and enhance value.
Contribute to broader research goals in areas related to biophysical chemistry aimed at developing a better understanding of therapeutic protein structure, stability, dynamics, and function.
Provide biophysical characterization support for other scientists across Biotherapeutics Discovery; perform other tasks as assigned by manager in a timely manner.
Improve data quality, consistency, and throughput using automation and analysis scripts. Identify opportunities for innovative automation strategies to streamline operations and boost workflow efficiency.
Comply with all applicable regulations, perform all work in a safe manner; maintain proper records in accordance with SOP’s and policies.
Qualification
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Required
Master’s Degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline, OR Bachelor’s Degree from an accredited institution with seven-plus (7+) years of experience in related scientific discipline or equivalent experience in related field
Extensive hands-on experience with chromatographic, spectroscopic, electrophoretic, calorimetric, or other advanced protein characterization techniques with several years of experience conducting biophysical techniques in the context of biotherapeutic discovery and/or development.
Experience conducting protein biophysical techniques in the context of biotherapeutic discovery and/or development, including accelerated stability/forced degradation studies.
Previous work in protein expression and purification.
Strong grasp of physical chemical/thermodynamic principles underpinning protein structure and stability, biotherapeutic quality attributes, CMC requirements, and QbD principles.
Creative problem solving with a high level of initiative and ability to work independently as well as collaboratively
Good record-keeping and organizational skills with exceptional attention to detail.
Excellent writing, presenting, and communicating skills.
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required).
Must be 18 years of age or older.
Preferred
Experience with lab automation; in-depth knowledge (programming, troubleshooting) is preferred.
Experience with data analysis software and/or modern computer programming languages (MATLAB, Mathematica, Python, SQL, or Java); experience in statistical and DOE software (JMP, R, Minitab, Statistica) is beneficial.
Benefits
Health Insurance
Company
Boehringer Ingelheim
Boehringer Ingelheim is a group of pharmaceutical companies that focuses on prescription medicines and animal health. It is a sub-organization of Boehringer Ingelheim.
Funding
Current Stage
Late StageRecent News
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